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作者:Liliya Logoyda , Dmytro Korobko , Oleksandra Oleshchuk ...
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (2), pp.31-40IAS
摘要:Objective: A highly specific, sensitive and rapid HPLC-MS/MS method has been developed and validated for the simultaneous quantification of bisoprolol and enalapril in the present of enalaprilat in human plasma.Methods: Analytes were extracted from plasma using a protein pre...
作者:Nasrul Wathoni , Aliya Nur Hasanah , Ahmed Fouad Abdelwahab Mohammed ...
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (2), pp.57-61IAS
摘要:Objective: The main objective of the research work was to fabricate sacran hydrogel film containing keratinocyte growth factor (Sacran/KGF-HGF), and to evaluate their wound healing ability in alloxan-induced diabetic mice model.Methods: The physicochemical characterization o...
作者:Ashutosh Roda , Prabhakara Prabhu , Akhilesh Dubey
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (2), pp.105-112IAS
摘要:Objective: Buccal patch is a non-dissolving thin matrix modified release dosage form which was developed to administer into the unconscious and less co-operative patients.Methods: The mucoadhesive buccal patches of hydrochlorothiazide (HCZ) and atenolol (ATN) were prepared by sol...
作者:Revathy B. Menon , Lakshmi V. S. , Aiswarya M. U. ...
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (2), pp.1-6IAS
摘要:A novel drug delivery system is the one that ensures optimum dose at the right time, at the right location. Porphysomes are among those drug delivery systems. Porphysomes are a means of vesicular drug delivery systems. They are liposome-like structures composed completely of porp...
作者:Sultana Gani Mohd Shaikh , Vandana Jain
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (2), pp.97-104IAS
摘要:Objective: To develop a novel, accurate, precise and linear reverse phase high performance liquid chromatographic (RP-HPLC) method for simultaneous quantitative estimation of gabapentin and amitriptyline hydrochloride in gabantip-at tablet and validate as per international c...
作者:Amol A. Tatode , Arun T. Patil , Milind J. Umekar
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (2), pp.62-69IAS
摘要:Objective: The present investigation was aimed to optimize the formula of paclitaxel-loaded liposomes (PTL) by using the application of response surface methodology (RSM).Methods: Paclitaxel-loaded liposome (PTL) was optimized by response surface methodology based on two par...
作者:Nazia Khanam , Md Irshad Alam , Quazi Md Aamer Iqbal Md Yusuf Ali ...
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (2), pp.7-12IAS
摘要:The present review article aims at determining the various possible techniques available to enhance the quality, safety and efficacy of pharmaceutical formulations by exploring most suitable and practically applicable experimental designs and optimization techniques. As we know t...
作者:Ahmed M. Samy , Afaf A. Ramadan , Amal S.m. Abu El-enin ...
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (2), pp.41-51IAS
摘要:Objective: The aim of the present study was to obtain an optimized formula of itraconazole (ITC) proniosomes using Box Behnken design.Methods: Itraconazole proniosomes were prepared using span 60 and/or brij 35 as surfactants, cholesterol and lecithin as a penetration enhancer by...
作者:Robert Tungadi , Arlan K. Imran
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (2), pp.70-75IAS
摘要:Objective: Snakehead fish has been scientifically proven to increase levels of albumin and boost the immune system so that the formulation development is required. The objective of this study was to formulate and characterize snakehead fish powder (SFP) in the form of the or...
作者:G. B. Preethi , H. N. Shivakumar , M Ravi Kumar ...
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (2), pp.13-19IAS
摘要:Objective: Lipid-based formulations have gained much attention, particularly on self-emulsifying drug delivery systems (SEDDS), to improve the oral bioavailability of lipophilic drugs. In the present study, an attempt was made to develop and evaluate prototype SEDDS of poorl...

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