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作者:Ilaria Genovese , Andrea Ilari , Theo Battista ...
来源:[J].Cancer Drug Resistance, 2018, Vol.1 (8)OAE
摘要:Soluble resistance-related calcium binding protein (Sorcin) is a protein initially labelled “resistance-related”, since it is co-amplified with ABCB1 in multidrug (MD)-resistant cells. While for years Sorcin overproduction was believed to be a by-product of the co-amplificat...
作者:Nicole B. Quenelle , Carrie L. Costantini
来源:[J].Journal of Unexplored Medical Data, 2018, Vol.3 (8)OAE
摘要:This article aims to review the role of immunotherapy in tumors of the head and neck, focusing primarily on US Food and Drug Administration (FDA) approved checkpoint inhibitors in squamous cell histology. The data showing superiority of checkpoint inhibitors over cytotoxic c...
作者:Somnath Mondal , Ankur Datta , Iman Hazra ...
来源:[J].Neuroimmunology and Neuroinflammation, 2018, Vol.5 (8)OAE
摘要:Aim: T11TS, a potent anti-gliomagenic glycoprotein, stimulates both peripheral and intracranial immune response. The status of bone marrow hematopoietic stem cells (BMHSCs), the cradle of regeneration of all blood cells, during gliomagenic global immune devastations has not yet b...
作者:Claire Morgan , Lucy J. Swithenbank , Helen Whiteland ...
来源:[J].Journal of Cancer Metastasis and Treatment, 2018, Vol.4 (8)OAE
摘要:Aim: The effects of hepatocyte growth factor (HGF) on a non-invasive prostate cancer cell line (CAHPV-10), expressing cMET were studied, to mimic the possible effects neo-adjuvant androgen deprivation therapy may have in promoting tumour progression. Methods: Prostate epithelial ...
作者:Lacey Boshe , A. Katherine M. Foreman , Jennifer L. Goldstein ...
来源:[J].Journal of Translational Genetics and Genomics, 2018, Vol.2 (8)OAE
摘要:Aim: To investigate the potential relationship between the strength of evidence for a gene-disease association and inclusion of the gene on a targeted, indication-based gene panel test for hereditary long QT syndrome (LQTS) and to explore factors that may influence laboratory dec...
作者:Natalia J. Gurule , Lynn E. Heasley
来源:[J].Cancer Drug Resistance, 2018, Vol.1 (8)OAE
摘要:Receptor tyrosine kinases (RTKs) bearing oncogenic mutations in EGFR, ALK and ROS1 occur in a significant subset of lung adenocarcinomas. Tyrosine kinase inhibitors (TKIs) targeting tumor cells dependent on these oncogenic RTKs yield tumor shrinkage, but also a variety of adverse...
作者:Benjamin Ziegler , Gabriel Hundeshagen , Tomke Cordts ...
来源:[J].Plastic and Aesthetic Research, 2018, Vol.5 (8)OAE
摘要:Surgical treatment of deep partial thickness to full thickness burn wounds by knife has been the undisputed standard of care and was one key point in surgical burn medicine for decades. Recently, it gets more and more challenged by Bromelain-based enzymatic burn wound debridement...
作者:Waldemar Schreiner , Wojciech Dudek , Denis Iulian Trufa ...
来源:[J].Plastic and Aesthetic Research, 2018, Vol.5 (8)OAE
摘要:Aim: Sternoclavicular joint infection associated with liver cirrhosis is an uncommon condition and the optimal surgical treatment is undefined. Methods: Patients and methods: we retrospectively analysed data from six patients with sternoclavicular joint infections and liver cirrh...
作者:Henry Zhao , Satomi Okano , Anita Pelecanos ...
来源:[J].Mini-invasive Surgery, 2018, Vol.2 (8)OAE
摘要:Aim: To retrospectively evaluate the safety and efficacy of repeat thermal ablation for local progression of lung tumours after prior ablation(s). Methods: From December 2009 to March 2017, 13 patients underwent repeat ablation [11 repeat microwave ablations and 2 repeat radiofre...
作者:Akhil Padarti , Jun Zhang
来源:[J].Vessel Plus, 2018, Vol.2 (8)OAE
摘要:Cerebral cavernous malformations (CCM) are manifested by microvascular lesions characterized by leaky endothelial cells with minimal intervening parenchyma predominantly in the central nervous system predisposed to hemorrhagic stroke, resulting in focal neurological defects. Till...

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