欧洲呼吸学会
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作者:Bernard Mari , Bruno Crestani
来源:[J].European Respiratory Journal(IF 6.355), 2019, Vol.54 (2)ERS
摘要:Unravelling the cellular and molecular mechanisms associated with the initiation and progression of idiopathic pulmonary fibrosis (IPF) represents a huge challenge. A better knowledge of these issues is not only imperative for elucidating the pathogenic mechanisms of IPF but...
作者:Meindina G. Haarman , Wilhelmina S. Kerstjens-Frederikse , Rolf M.F. Berger
来源:[J].European Respiratory Journal(IF 6.355), 2019, Vol.54 (2)ERS
摘要:Transcription factors of the T-box family are known to be involved in the regulation of embryonic developmental processes. T-box factor 4 (TBX4), one of its members first discovered in 1996, is expressed in a wide variety of tissues during organogenesis [1, 2]. The TBX4 gene is l...
作者:Antonella LoMauro , Paolo Banfi , Maria Grazia D'Angelo ...
来源:[J].European Respiratory Journal(IF 6.355), 2019, Vol.54 (2)ERS
摘要:Glossopharyngeal breathing (GPB), also called “frog breathing”, is a positive pressure breathing technique that uses muscles of the mouth and pharynx to propel small volumes of air (“gulps”) into the lungs. It consists of three phases: 1) mouth opening so that air enter...
作者:Hille Suojalehto , Katri Suuronen , Paul Cullinan
来源:[J].European Respiratory Journal(IF 6.355), 2019, Vol.54 (2)ERS
摘要:When undertaken carefully, and in experienced hands, specific inhalation challenge (SIC) testing is widely considered to be the reference standard in the diagnosis of occupational asthma. In 2013 the European Respiratory Society commissioned a pan-European task force to produce s...
作者:Csaba Galambos , Mary P. Mullen , Joseph T. Shieh ...
来源:[J].European Respiratory Journal(IF 6.355), 2019, Vol.54 (2)ERS
摘要:Rare variants in the T-box transcription factor 4 gene ( TBX4 ) have recently been recognised as an emerging cause of paediatric pulmonary hypertension (PH). Their pathophysiology and contribution to persistent pulmonary hypertension in neonates (PPHN) are unknown. We sought to d...
作者:Christina Morse , Tracy Tabib , John Sembrat ...
来源:[J].European Respiratory Journal(IF 6.355), 2019, Vol.54 (2)ERS
摘要:A comprehensive understanding of the changes in gene expression in cell types involved in idiopathic pulmonary fibrosis (IPF) will shed light on the mechanisms underlying the loss of alveolar epithelial cells and development of honeycomb cysts and fibroblastic foci. We sought to ...
作者:Bin Jiang , Xue-lian Li , Yan Yin ...
来源:[J].European Respiratory Journal(IF 6.355), 2019, Vol.54 (2)ERS
摘要:Introduction(#br)Traditional thoracic ultrasound (TUS) is often the initial tool used to help diagnose malignant pleural effusion (MPE). Ultrasound elastography, a relatively new technique, has been used to differentiate malignant disease from benign disease by evaluating ti...
作者:Hayoung Choi , Bumhee Yang , Hyewon Nam ...
来源:[J].European Respiratory Journal(IF 6.355), 2019, Vol.54 (2)ERS
摘要:Bronchiectasis is a chronic respiratory disease characterised by abnormal dilatation of bronchi, which presents clinically with cough, sputum production and recurrent infection [1]. Although bronchiectasis had been regarded as an “orphan” disease [2], recent studies have sho...
作者:Kristina Laubhahn , Bianca Schaub
来源:[J].European Respiratory Journal(IF 6.355), 2019, Vol.54 (2)ERS
摘要:Asthma is a heterogeneous chronic inflammatory disease of the airways with variety of different phenotypes and is most frequently classified according to clinical phenotypes into allergic and non-allergic asthma [1] or according to severity into intermittent, mild, moderate or se...
作者:Dan Adler , Antoine Poncet , Ruxandra Iancu Ferfoglia ...
来源:[J].European Respiratory Journal(IF 6.355), 2019, Vol.54 (2)ERS
摘要:Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive neurodegenerative disease that affects the brain and spinal cord motor neurons leading to progressive muscle weakness, irreversible disability, respiratory failure and death within a time range of a few months to m...

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