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作者:Chanda Gupta , Roy Tan , Chitaranjan Mishra ...
来源:[J].PLOS ONE(IF 3.73), 2018, Vol.13 (12)PLOS
摘要:To evaluate structural changes in the choroid among patients with diabetic macular edema (DME), with varying grades of diabetic retinopathy (DR), using enhance depth imaging spectral domain optical coherence tomography (EDI SD-OCT) scans.;;A cross-sectional study was conduct...
作者:Mingshu Shi , Øyvind Ellingsen , Tone Frost Bathen ...
来源:[J].PLOS ONE(IF 3.73), 2018, Vol.13 (12)PLOS
摘要:Exercise training increases aerobic capacity and is beneficial for health, whereas low aerobic exercise capacity is a strong independent predictor of cardiovascular disease and premature death. The purpose of the present study was to determine the metabolic profiles in a rat mode...
作者:Shotaro Masuoka , Natsuko Kusunoki , Ryo Takamatsu ...
来源:[J].PLOS ONE(IF 3.73), 2018, Vol.13 (12)PLOS
摘要:The objective of the present study was to investigate Epstein-Barr virus (EBV) infection as an environmental factor for the development of rheumatoid arthritis (RA).;;Synovial tissues were collected during surgery from 128 RA and 98 osteoarthritis (OA) patients. DNA was extracted...
作者:Karl Grieshop , Göran Arnqvist
来源:[J].PLOS Biology(IF 11.452), 2018, Vol.16 (12)PLOS
摘要:The maintenance of genetic variance in fitness represents one of the most longstanding enigmas in evolutionary biology. Sexually antagonistic (SA) selection may contribute substantially to maintaining genetic variance in fitness by maintaining alternative alleles with opposi...
作者:Raju Sunagar , Sudeep Kumar , Prachi Namjoshi ...
来源:[J].PLOS ONE(IF 3.73), 2018, Vol.13 (12)PLOS
摘要:Francisella tularensis ( Ft ) is a biothreat agent for which there is no FDA-approved human vaccine. Currently, there are substantial efforts underway to develop both vaccines and the tools to assess these vaccines. Tularemia laboratory research has historically relied prima...
作者:Silvia Da Ros , Luca Aresu , Serena Ferraresso ...
来源:[J].PLOS ONE(IF 3.73), 2018, Vol.13 (12)PLOS
摘要:Despite canine B-cell Lymphoma (BCL) representing the most common haematological tumour, epigenetic events driving development and progression are scarcely known. Recently, canine Diffuse Large BCL (DLBCL) DNA methylome by genome-wide CpG microarray has identified genes and pathw...
作者:Trang Quynh Nguyen , Benjamin Ackerman , Ian Schmid ...
来源:[J].PLOS ONE(IF 3.73), 2018, Vol.13 (12)PLOS
摘要:Randomized controlled trials are often used to inform policy and practice for broad populations. The average treatment effect (ATE) for a target population, however, may be different from the ATE observed in a trial if there are effect modifiers whose distribution in the tar...
作者:Tingkun Chen , Qian Cong , Jingfu Jin ...
来源:[J].PLOS ONE(IF 3.73), 2018, Vol.13 (12)PLOS
摘要:The present work investigates the process of frosting formation on arched copper samples with different surface temperatures, calculated the thickness of the frost layer by using the scale method, and analyzed frost lodging, melting, and other phenomena that appeared during ...

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