科学公共图书馆
期刊
会议
图书
作者:Laura V. Glaser , Simone Rieger , Sybille Thumann ...
来源:[J].PLOS Pathogens(IF 9.127), 2017, Vol.13 (10)PLOS
摘要:Epstein-Barr virus (EBV) infection converts resting human B cells into permanently proliferating lymphoblastoid cell lines (LCLs). The Epstein-Barr virus nuclear antigen 2 (EBNA2) plays a key role in this process. It preferentially binds to B cell enhancers and establishes a spec...
作者:Alejandro Javier Krolewiecki , Maria Cristina Almazan , Marcelo Quipildor ...
来源:[J].PLOS Neglected Tropical Diseases(IF 4.569), 2017, Vol.11 (10)PLOS
摘要:Leishmania ( Viannia ) braziliensis is the species most frequently implicated with cutaneous and mucosal leishmaniasis in the Americas; its diagnosis is based on the identification of amastigotes in lesions, which is limited by low parasite burden. Leishmanin Skin Test (LST)...
作者:Agne Tilūnaitė , Wayne Croft , Noah Russell ...
来源:[J].PLOS Computational Biology(IF 5.215), 2017, Vol.13 (10)PLOS
摘要:Calcium responses have been observed as spikes of the whole-cell calcium concentration in numerous cell types and are essential for translating extracellular stimuli into cellular responses. While there are several suggestions for how this encoding is achieved, we still lack a co...
作者:Thomas Heidlauf , Thomas Klotz , Christian Rode ...
来源:[J].PLOS Computational Biology(IF 5.215), 2017, Vol.13 (10)PLOS
摘要:Contractions on the descending limb of the total (active + passive) muscle force—length relationship (i. e. when muscle stiffness is negative) are expected to lead to vast half-sarcomere—length inhomogeneities. This is however not observed in experiments—vast half-sarco...
作者:Oliver Bärenbold , Giovanna Raso , Jean T. Coulibaly ...
来源:[J].PLOS Neglected Tropical Diseases(IF 4.569), 2017, Vol.11 (10)PLOS
摘要:The Kato-Katz technique is the most widely used diagnostic method in epidemiologic surveys and drug efficacy trials pertaining to intestinal schistosomiasis and soil-transmitted helminthiasis. However, the sensitivity of the technique is low, particularly for the detection o...
作者:Katherine M. Gass , Heven Sime , Upendo J. Mwingira ...
来源:[J].PLOS Neglected Tropical Diseases(IF 4.569), 2017, Vol.11 (10)PLOS
摘要:Endemicity mapping is required to determining whether a district requires mass drug administration (MDA). Current guidelines for mapping LF require that two sites be selected per district and within each site a convenience sample of 100 adults be tested for antigenemia or mi...
作者:Molly Parkyn Schneider , Boyin Liu , Philipp Glock ...
来源:[J].PLOS Pathogens(IF 9.127), 2017, Vol.13 (10)PLOS
摘要:Transmission of malaria parasites relies on the formation of a specialized blood form called the gametocyte. Gametocytes of the human pathogen, Plasmodium falciparum , adopt a crescent shape. Their dramatic morphogenesis is driven by the assembly of a network of microtubules and ...
作者:Jaymar Soriano , Takatomi Kubo , Takao Inoue ...
来源:[J].PLOS Computational Biology(IF 5.215), 2017, Vol.13 (10)PLOS
摘要:Experiments with drug-induced epilepsy in rat brains and epileptic human brain region reveal that focal cooling can suppress epileptic discharges without affecting the brain’s normal neurological function. Findings suggest a viable treatment for intractable epilepsy cases vi...
作者:David R. Soto , Christopher Barton , Karl Munger ...
来源:[J].PLOS Pathogens(IF 9.127), 2017, Vol.13 (10)PLOS
摘要:Expression of E7 proteins encoded by carcinogenic, high-risk human papillomaviruses (HPVs) triggers increased expression of the histone H3 lysine 27 demethylase KDM6A. KDM6A expression is necessary for survival of high-risk HPV E7 expressing cells, including several cervical...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×