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Cytogenetically Normal Acute Myeloid Leukemia with a Novel KIT Mutation in Exon 11 G565V Developing a Sole Trisomy 13 at Relapse: A Clinical Dilemma
作者：Nieto M.J. , Scalise A. , Najfeld V.
来源：[J].Acta Haematologica(IF 0.894), 2015, Vol.133 (1), pp.1-5Karger
摘要：We describe a patient with acute myeloid leukemia (AML) who had a normal karyotype at diagnosis and was negative for NPM1 and FLT3 mutations, but had a KIT G565V mutation in exon 11. This has not been described previously in AML. The patient received induction and consolidat...
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    L -Asparginase Administration Reduces White Blood Cell Count and Prevents Tumor Lysis Syndrome in Children with Hyperleukocytic Acute Lymphoblastic Leukemia
    作者：Sondhi V. , Sharma A. , Taneja M. ...
    来源：[J].Acta Haematologica(IF 0.894), 2015, Vol.133 (1), pp.6-9Karger
    摘要：Background: The management of hyperleukocytosis currently involves intensive supportive care for preventing tumor lysis syndrome (TLS)-associated metabolic abnormalities as well as cytoreduction procedures to reduce the white blood cell (WBC) count. These procedures are ofte...
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      Serum Lactate Dehydrogenase with a Systemic Inflammation Score Is Useful for Predicting Response and Survival in Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma
      作者：Jung S.-H. , Yang D.-H. , Ahn J.-S. ...
      来源：[J].Acta Haematologica(IF 0.894), 2015, Vol.133 (1), pp.10-17Karger
      摘要：We evaluated the relationship between serum lactate dehydrogenase (LDH) level with systemic inflammation score and survival in 213 patients with diffuse large B-cell lymphoma (DLBCL) receiving R-CHOP chemotherapy. The patients were classified into 3 groups based on LDH with ...
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        Arsenic Trioxide Inhibits DNA Methyltransferase and Restores TMS1 Gene Expression in K562 Cells
        作者：Li H. , Wang Y. , Xu W. ...
        来源：[J].Acta Haematologica(IF 0.894), 2015, Vol.133 (1), pp.18-25Karger
        摘要：Background: Gene silencing associated with aberrant methylation of promoter region CpG islands is an acquired epigenetic alteration that serves as an alternative to genetic defects in the inactivation of tumor suppressor genes in human cancers. The demethylating, dose-depend...
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          New Data on Subcutaneous Bortezomib
          作者：Moreau P. , Touzeau C.
          来源：[J].Acta Haematologica(IF 0.894), 2015, Vol.133 (1), pp.26-28Karger
          摘要：No abstract available
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            An Acceptable Incidence of Infusion Site Reactions after Subcutaneous Bortezomib Administration in the Upper Arm in Japanese Patients with Multiple Myeloma
            作者：Ohgiya D. , Tsuchiya T. , Suyama T. ...
            来源：[J].Acta Haematologica(IF 0.894), 2015, Vol.133 (1), pp.29-30Karger
            摘要：No abstract available
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              Effect of Vitamin D Replacement on Hemoglobin Concentration in Subjects with Concurrent Iron-Deficiency Anemia and Vitamin D Deficiency: A Randomized, Single-Blinded, Placebo-Controlled Trial
              作者：Sooragonda B. , Bhadada S.K. , Shah V.N. ...
              来源：[J].Acta Haematologica(IF 0.894), 2015, Vol.133 (1), pp.31-35Karger
              摘要：Background: The effect of vitamin D replacement on hemoglobin (Hb) concentration in subjects with concurrent deficiencies of vitamin D and iron is not known. Methods: We report on an investigator-initiated, randomized, single-blinded, placebo-controlled, 12-week intervention...
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                Changing Concepts of Diagnostic Criteria of Myeloproliferative Disorders and the Molecular Etiology and Classification of Myeloproliferative Neoplasms: From Dameshek 1950 to Vainchenker 2005 and Beyond
                作者：Michiels J.J. , Berneman Z. , Schroyens W. ...
                来源：[J].Acta Haematologica(IF 0.894), 2015, Vol.133 (1), pp.36-51Karger
                摘要：The Polycythemia Vera Study Group (PVSG) and WHO classifications distinguished the Philadelphia (Ph1) chromosome-positive chronic myeloid leukemia from the Ph1-negative myeloproliferative neoplasms (MPN) essential thrombocythemia (ET), polycythemia vera...
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                  Essential Differences in Clinical and Bone Marrow Features in BCR/ABL- Positive Thrombocythemia Compared to Thrombocythemia in the BCR/ABL -Negative Myeloproliferative Neoplasms Essential Thrombocythemia and Polycythemia Vera
                  作者：Michiels J.J. , Pich A. , De Raeve H. ...
                  来源：[J].Acta Haematologica(IF 0.894), 2015, Vol.133 (1), pp.52-55Karger
                  摘要：No abstract available
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                    Aspirin-Responsive, Migraine-Like Transient Cerebral and Ocular Ischemic Attacks and Erythromelalgia in JAK2-Positive Essential Thrombocythemia and Polycythemia Vera
                    作者：Michiels J.J. , Berneman Z. , Gadisseur A. ...
                    来源：[J].Acta Haematologica(IF 0.894), 2015, Vol.133 (1), pp.56-63Karger
                    摘要：Migraine-like cerebral transient ischemic attacks (MIAs) and ocular ischemic manifestations were the main presenting features in 10 JAK2V617F-positive patients studied, with essential thrombocythemia (ET) in 6 and polycythemia vera (PV) in 4. Symptoms varied and i...
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