Future Science Group期刊
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作者:Harriet Wall
来源:[J].Future Med. Chem.(IF 3.31), 2020, Vol.12 (1), pp.1-3Future Science Group
作者:Jian Ming , Yabing Zhang , Xun Xu ...
来源:[J].J. Comp. Eff. Res., 2020, pp.-Future Science Group
摘要:Aim: To evaluate the cost–effectiveness of intravitreal aflibercept compared with macular laser photocoagulation and ranibizumab for diabetic macular edema (DME) in China. Methods: A Markov model was developed to reflect the vision changes in DME patients. Parameters were es...
作者:Murari Gurjar , Parsshava Mehta , Jyoti Sharma ...
来源:[J].Bioanalysis(IF 3.253), 2020, Vol.12 (2), pp.75-85Future Science Group
摘要:Aim: To develop a sensitive HPLC method for the quantitation of sunitinib (SU) and its active metabolite N-desethyl-sunitinib (SU12662) in human plasma. Materials & methods: The analytes were extracted from 500 μl of plasma using liquid–liquid extraction followed by protein ...
作者:John Aaron Howell , Gene L Bidwell
来源:[J].Ther. Deliv., 2020, pp.-Future Science Group
摘要:Ischemic strokes occur when a major cerebral artery or its branches are occluded, resulting in activation of inflammatory processes that cause secondary tissue injury, breakdown of the blood–brain barrier, edema or hemorrhage. Treatments that inhibit inflammatory processes m...
作者:Anhye Kim , Stephen R Dueker , Feng Dong ...
来源:[J].Bioanalysis(IF 3.253), 2020, Vol.12 (2), pp.87-98Future Science Group
摘要:Aim: Human 14C radiotracer studies provide information-rich data sets that enable informed decision making in clinical drug development. These studies are supported by liquid scintillation counting after conventional-sized 14C doses (50–200 μCi) or complex accelerator mass s...
作者:Su-jin Yang , Dan-dan Wang , Si-ying Zhou ...
来源:[J].Epigenomics(IF 2.433), 2020, pp.-Future Science Group
摘要:Aim: Circular RNAs (circRNAs) still have many potential functions in the process of tumor development that are not completely understood. The study aims to explore novel circRNAs and their mechanisms of action in breast cancer (BCa). Materials & methods: A combination strate...
作者:Sarah Yenser Wood , Joanne C Ryan , Andrew G Clair ...
来源:[J].Future Oncol.(IF 3.202), 2020, pp.-Future Science Group
摘要:Until recently, the sole treatment for patients with nonmetastatic renal cell carcinoma (RCC) was nephrectomy followed by observation. As metastatic RCC (mRCC) remains largely incurable (5-year survival rate ∼12%), adjuvant treatment, with potential to prevent/delay disease ...
作者:Si-ying Zhou , Wei Chen , Su-jin Yang ...
来源:[J].Epigenomics(IF 2.433), 2020, pp.-Future Science Group
摘要:Aim: We aimed to explore the roles of circular RNA, circVAPA in regulating cell migration and invasion of breast cancer. Materials & methods: CircVAPA expression was detected in breast cancer tissues and cells. The role of circVAPA was evaluated by MTT assay, wound-healing and tr...
作者:Ian S Fentiman
来源:[J].Breast Cancer Manag., 2020, pp.-Future Science Group
摘要:Male breast cancer (MBC) is rare, tending to afflict sedentary men, with adolescent obesity being a risk factor. Men fare worse compared with matched females with breast cancer. The preponderance of ER+ve disease affects the molecular profile: most cases have luminal A tumors. Th...
作者:Hiroshige Yoshioka , Terufumi Kato , Isamu Okamoto ...
来源:[J].Future Oncol.(IF 3.202), 2020, pp.-Future Science Group
摘要:Aim: Acquired resistance to EGFR tyrosine kinase inhibitors is inevitable in non-small-cell lung cancer. To inform subsequent treatment decisions, we retrospectively assessed therapies following afatinib in Japanese patients from LUX-Lung 3. Patients & methods: LUX-Lung 3 wa...

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