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A ‘devil’ of a problem
作者：Victoria L Hansen , Robert D Miller
来源：[J].eLife, 2018, Vol.7eLife科学出版社
摘要：The discovery of a second facial tumor disease in the Tasmanian devil has provided insights into the emergence of contagious cancers.
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    Framing orientation selectivity
    作者：Floris P de Lange , Matthias Ekman
    来源：[J].eLife, 2018, Vol.7eLife科学出版社
    摘要：The ongoing debate on the neural basis of orientation selectivity in the primary visual cortex continues.
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      Stimulus vignetting and orientation selectivity in human visual cortex
      作者：Zvi N Roth , David J Heeger , Elisha P Merriam
      来源：[J].eLife, 2018, Vol.7eLife科学出版社
      摘要：Neural selectivity to orientation is one of the simplest and most thoroughly-studied cortical sensory features. Here, we show that a large body of research that purported to measure orientation tuning may have in fact been inadvertently measuring sensitivity to second-order ...
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        The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer
        作者：Alison Caldwell , Rachel Coleby , Cesar Tovar ...
        来源：[J].eLife, 2018, Vol.7eLife科学出版社
        摘要：Devil Facial Tumour 2 (DFT2) is a recently discovered contagious cancer circulating in the Tasmanian devil ( Sarcophilus harrisii ), a species which already harbours a more widespread contagious cancer, Devil Facial Tumour 1 (DFT1). Here we show that in contrast to DFT1, DFT...
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          A multispecies coalescent model for quantitative traits
          作者：Fábio K Mendes , Jesualdo A Fuentes-González , Joshua G Schraiber ...
          来源：[J].eLife, 2018, Vol.7eLife科学出版社
          摘要：We present a multispecies coalescent model for quantitative traits that allows for evolutionary inferences at micro- and macroevolutionary scales. A major advantage of this model is its ability to incorporate genealogical discordance underlying a quantitative trait. We show ...
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            Using paired serology and surveillance data to quantify dengue transmission and control during a large outbreak in Fiji
            作者：Adam J Kucharski , Mike Kama , Conall H Watson ...
            来源：[J].eLife, 2018, Vol.7eLife科学出版社
            摘要：Dengue is a major health burden, but it can be challenging to examine transmission and evaluate control measures because outbreaks depend on multiple factors, including human population structure, prior immunity and climate. We combined population-representative paired sera ...
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              Functional gradients of the cerebellum
              作者：Xavier Guell , Jeremy D Schmahmann , John DE Gabrieli ...
              来源：[J].eLife, 2018, Vol.7eLife科学出版社
              摘要：A central principle for understanding the cerebral cortex is that macroscale anatomy reflects a functional hierarchy from primary to transmodal processing. In contrast, the central axis of motor and nonmotor macroscale organization in the cerebellum remains unknown. Here we appli...
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                Dynamic density shaping of photokinetic E. coli
                作者：Giacomo Frangipane , Dario Dell'Arciprete , Serena Petracchini ...
                来源：[J].eLife, 2018, Vol.7eLife科学出版社
                摘要：Many motile microorganisms react to environmental light cues with a variety of motility responses guiding cells towards better conditions for survival and growth. The use of spatial light modulators could help to elucidate the mechanisms of photo-movements while, at the same...
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                  A transient cortical state with sleep-like sensory responses precedes emergence from general anesthesia in humans
                  作者：Laura D Lewis , Giovanni Piantoni , Robert A Peterfreund ...
                  来源：[J].eLife, 2018, Vol.7eLife科学出版社
                  摘要：During awake consciousness, the brain intrinsically maintains a dynamical state in which it can coordinate complex responses to sensory input. How the brain reaches this state spontaneously is not known. General anesthesia provides a unique opportunity to examine how the hum...
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                    Efficient analysis of mammalian polysomes in cells and tissues using Ribo Mega-SEC
                    作者：Harunori Yoshikawa , Mark Larance , Dylan J Harney ...
                    来源：[J].eLife, 2018, Vol.7eLife科学出版社
                    摘要：We describe Ribo Mega-SEC, a powerful approach for the separation and biochemical analysis of mammalian polysomes and ribosomal subunits using Size Exclusion Chromatography and uHPLC. Using extracts from either cells, or tissues, polysomes can be separated within 15 min from samp...
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