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The mechanisms of graphene-based materials-induced programmed cell death: a review of apoptosis, autophagy, and programmed necrosis
作者：Lingling Ou , Shaoqiang Lin , Bin Song ...
来源：[J].International Journal of Nanomedicine(IF 3.463), 2017, Vol.2017 (default), pp.6633-6646Dove
摘要：Graphene-based materials (GBMs) are widely used in many fields, including biomedicine. To date, much attention had been paid to the potential unexpected toxic effects of GBMs. We review the recent literature regarding the impact of GBMs on programmed cell death (PCD). Apopto...
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    Delivery of paeonol by nanoparticles enhances its in vitro and in vivo antitumor effects
    作者：Cong Chen , Feng Jia , Zhibo Hou ...
    来源：[J].International Journal of Nanomedicine(IF 3.463), 2017, Vol.2017 (default), pp.6605-6616Dove
    摘要：Paeonol (Pae; 2'-hydroxy-4'-methoxyacetophenone) has attracted intense attention as a potential therapeutic agent against various cancers. However, the use of Pae is limited owing to its hydrophobicity. Recently, biodegradable polymeric nanoparticles with amphiphilic copolymers h...
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      Autophagy promotes degradation of polyethyleneimine–alginate nanoparticles in endothelial progenitor cells
      作者：Guo-dong Wang , Yu-zhen Tan , Hai-jie Wang ...
      来源：[J].International Journal of Nanomedicine(IF 3.463), 2017, Vol.2017 (default), pp.6661-6675Dove
      摘要：Polyethyleneimine-alginate nanoparticle (PEI-Alg NP) is a safe and effective vector for delivery of siRNA or DNA. Recent studies suggest that autophagy is related with cytotoxity of PEI NPs. However, contribution of autophagy to degradation of PEI-Alg NPs remains unknown. CD34+VE...
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        Pharmacovigilance and adverse drug reaction reporting: a perspective of community pharmacists and pharmacy technicians in Sana’a, Yemen
        作者：Yaser Mohammed Al-Worafi , Yaman Walid Kassab , Wafa Mohammed Alseragi ...
        来源：[J].Therapeutics and Clinical Risk Management, 2017, Vol.2017 (default), pp.1175-1181Dove
        摘要：ObjectivesThe aim of this study was to compare the knowledge, attitude and barriers of pharmacy technicians and pharmacists towards pharmacovigilance, ADRs and ADRs reporting in community pharmacies in Yemen.MethodsThis cross-sectional survey was conducted among community ph...
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          Synthetic high-density lipoprotein nanodisks for targeted withalongolide delivery to adrenocortical carcinoma
          作者：Rui Kuai , Chitra Subramanian , Peter T White ...
          来源：[J].International Journal of Nanomedicine(IF 3.463), 2017, Vol.2017 (default), pp.6581-6594Dove
          摘要：Adrenocortical carcinoma (ACC) is a rare endocrine malignancy and has a five-year survival rate of less than 35%. ACC cells require cholesterol for steroid hormone production, and this requirement is met via expression on the cell surface of a high level of the scavenger rec...
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            Polymeric mixed micelles loaded mitoxantrone for overcoming multidrug resistance in breast cancer via photodynamic therapy
            作者：Zeyong Li , Yuee Cai , Yiqiao Zhao ...
            来源：[J].International Journal of Nanomedicine(IF 3.463), 2017, Vol.2017 (default), pp.6595-6604Dove
            摘要：Mitoxantrone (MIT) is an anticancer agent with photosensitive properties commonly used in various cancers. Multidrug resistance (MDR) effect has been an obstacle to using MIT for cancer therapy. Photochemical internalization, on account of photodynamic therapy, has been appl...
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              Five-year durability of stand-alone interspinous process decompression for lumbar spinal stenosis
              作者：Pierce D. Nunley , Vikas V. Patel , Douglas Orndorff, M.D. ...
              来源：[J].Clinical Interventions in Aging, 2017, Vol.2017 (default), pp.1409-1417Dove
              摘要：Background: Lumbar spinal stenosis is the most common indication for spine surgery in older adults. Interspinous process decompression (IPD) using a stand-alone spacer that functions as an extension blocker offers a minimally-invasive treatment option for intermittent neurog...
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                Combination of palladium nanoparticles and tubastatin-A potentiates apoptosis in human breast cancer cells: a novel therapeutic approach for cancer
                作者：Yu-Guo Yuan , Qiu-Ling Peng , Sangiliyandi Gurunathan
                来源：[J].International Journal of Nanomedicine(IF 3.463), 2017, Vol.2017 (default), pp.6503-6520Dove
                摘要：BackgroundBreast cancer is the most common malignant disease in women. Histone deacetylase (HDAC) inhibition has recently emerged as an effective and attractive target for the treatment of cancer. The aim of this study was to investigate the efficacy of a combined treatment ...
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                  The challenge of perioperative pain management in opioid-tolerant patients
                  作者：Flaminia Coluzzi , Francesca Bifulco , Arturo Cuomo ...
                  来源：[J].Therapeutics and Clinical Risk Management, 2017, Vol.2017 (default), pp.1163-1173Dove
                  摘要：The increasing number of opioid users among chronic pain patients and opioid abusers among general population made health care professionals more likely to manage perioperative pain in such a challenging setting. Anaesthesiologists, surgeons and nurses should be familiar with som...
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                    Evaluating the antiemetic administration consistency to prevent chemotherapy-induced nausea and vomiting with the standard guidelines: a prospective observational study
                    作者：Afsaneh Vazin , Davood Eslami , Ebrahim Sahebi
                    来源：[J].Therapeutics and Clinical Risk Management, 2017, Vol.2017 (default), pp.1151-1157Dove
                    摘要：Nausea and vomiting are of the most prevalent adverse effects of Chemotherapy. This study was conducted to evaluate adherence of health-care team to standard guidelines of antiemetics usage to prevent acute chemotherapy induced nausea and vomiting in a large chemotherapy Center.A...
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