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作者:John-Demian Sauer , Anat A. Herskovits , Mary X.D. O’Riordan ...
来源:[J].Microbiology Spectrum, 2019, Vol.7 (4)ASM Press
摘要:Bacterial metabolism represents the biochemical space that bacteria can manipulate to produce energy, reducing equivalents and building blocks for replication. Gram-positive pathogens, such as Listeria monocytogenes, show remarkable flexibility, which allows for exploitation of d...
作者:Ananias A. Escalante , M. Andreína Pacheco , Lee W. Riley ...
来源:[J].Microbiology Spectrum, 2019, Vol.7 (4)ASM Press
摘要:Malaria is a vector-borne disease that involves multiple parasite species in a variety of ecological settings. However, the parasite species causing the disease, the prevalence of subclinical infections, the emergence of drug resistance, the scale-up of interventions, and the eco...
作者:Vincent J. C. van Winden , Edith N. G. Houben , Miriam Braunstein ...
来源:[J].Microbiology Spectrum, 2019, Vol.7 (4)ASM Press
摘要:Mycobacteria, including the infamous pathogen Mycobacterium tuberculosis, are high-GC Gram-positive bacteria with a distinctive cell envelope. Although there is a typical inner membrane, the mycobacterial cell envelope is unusual in having its peptidoglycan layer connected to a p...
作者:Jaqueline Goes de Jesus , Marta Giovanetti , Nuno Rodrigues Faria ...
来源:[J].Microbiology Spectrum, 2019, Vol.7 (4)ASM Press
摘要:The MinION sequencer was launched by the Oxford Nanopore Technologies start-up as a disruptive technology for genome sequencing based on single-molecule synthesis. Its characteristics as a portable device, low cost, and simple library preparation have made it a good candidate for...
作者:Vincent A. Fischetti , Vincent A. Fischetti , Richard P. Novick ...
来源:[J].Microbiology Spectrum, 2019, Vol.7 (4)ASM Press
摘要:Surface proteins are critical for the survival of gram-positive bacteria both in the environment and to establish an infection. Depending on the organism, their surface proteins are evolutionarily tailored to interact with specific ligands on their target surface, be it inanimate...
作者:Madeleine W. Cunningham , Vincent A. Fischetti , Richard P. Novick ...
来源:[J].Microbiology Spectrum, 2019, Vol.7 (4)ASM Press
摘要:The group A streptococci are associated with a group of diseases affecting the heart, brain, and joints that are collectively referred to as acute rheumatic fever. The streptococcal immune-mediated sequelae, including acute rheumatic fever, are due to antibody and cellular immune...
作者:Yunjie Chang , Jun Liu , Maria Sandkvist ...
来源:[J].Microbiology Spectrum, 2019, Vol.7 (4)ASM Press
摘要:Periplasmic flagella are complex nanomachines responsible for distinctive morphology and motility of spirochetes. Although bacterial flagella have been extensively studied for several decades in the model systems Escherichia coli and Salmonella enterica, our understanding of peri...
作者:Amalina Ghaisani Komarudin , Arnold J. M. Driessen , Maria Sandkvist ...
来源:[J].Microbiology Spectrum, 2019, Vol.7 (4)ASM Press
摘要:In bacteria, the Sec translocase mediates the translocation of proteins into and across the cytoplasmic membrane. It consists of a protein conducting channel SecYEG, the ATP-dependent motor SecA, and the accessory SecDF complex. Here we discuss the function and structure of the S...
作者:Masahiro Nagahama , Masaya Takehara , Julian I. Rood ...
来源:[J].Microbiology Spectrum, 2019, Vol.6 (4)ASM Press
摘要:The pathogenesis of clostridial myonecrosis or gas gangrene involves an interruption to the blood supply to the infected tissues, often via a traumatic wound, anaerobic growth of the infecting clostridial cells, the production of extracellular toxins, and toxin-mediated cell...
作者:Jennifer A. Bennett
来源:[J].Journal of Microbiology & Biology Education, 2019, Vol.20 (2)ASM Press
摘要:This study assesses the educational impact of virtual reality (VR) on student learning and engagement in a sophomore-level cell biology course taught at Otterbein University. Using VR, students toured the cell and its environment within the human body. Next, students completed a ...

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