Annual Reviews期刊
期刊
会议
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作者:Albert A. Davis , Cheryl E.G. Leyns , David M. Holtzman
来源:[J].Annual Review of Cell and Developmental Biology(IF 17.983), 2018, Vol.34, pp.545-568Annual Reviews
摘要:Most neurodegenerative diseases are characterized by the accumulation of protein aggregates, some of which are toxic to cells. Mounting evidence demonstrates that in several diseases, protein aggregates can pass from neuron to neuron along connected networks, although the role of...
作者:Robert G. Parton
来源:[J].Annual Review of Cell and Developmental Biology(IF 17.983), 2018, Vol.34, pp.111-136Annual Reviews
摘要:The plasma membrane of eukaryotic cells is not a simple sheet of lipids and proteins but is differentiated into subdomains with crucial functions. Caveolae, small pits in the plasma membrane, are the most abundant surface subdomains of many mammalian cells. The cellular functions...
作者:Yukiko M. Yamashita , Mayu Inaba , Michael Buszczak
来源:[J].Annual Review of Cell and Developmental Biology(IF 17.983), 2018, Vol.34, pp.59-84Annual Reviews
摘要:In recent years, thin membrane protrusions such as cytonemes and tunneling nanotubes have emerged as a novel mechanism of intercellular communication. Protrusion-based cellular interactions allow for specific communication between participating cells and have a distinct spectrum ...
作者:C.E. Wagner , K.M. Wheeler , K. Ribbeck
来源:[J].Annual Review of Cell and Developmental Biology(IF 17.983), 2018, Vol.34, pp.189-215Annual Reviews
摘要:We review what is currently understood about how the structure of the primary solid component of mucus, the glycoprotein mucin, gives rise to the mechanical and biochemical properties of mucus that are required for it to perform its diverse physiological roles. Macroscale process...
作者:Ming-Ming Hu , Hong-Bing Shu
来源:[J].Annual Review of Cell and Developmental Biology(IF 17.983), 2018, Vol.34, pp.357-379Annual Reviews
摘要:Microbial nucleic acids are major signatures of invading pathogens, and their recognition by various host pattern recognition receptors (PRRs) represents the first step toward an efficient innate immune response to clear the pathogens. The nucleic acid–sensing PRRs are local...
作者:Carly R. Grant , Juan Wan , Arash Komeili
来源:[J].Annual Review of Cell and Developmental Biology(IF 17.983), 2018, Vol.34, pp.217-238Annual Reviews
摘要:Uncovering the mechanisms that underlie the biogenesis and maintenance of eukaryotic organelles is a vibrant and essential area of biological research. In comparison, little attention has been paid to the process of compartmentalization in bacteria and archaea. This lack of ...
作者:Edith Pierre-Jerome , Colleen Drapek , Philip N. Benfey
来源:[J].Annual Review of Cell and Developmental Biology(IF 17.983), 2018, Vol.34, pp.289-310Annual Reviews
摘要:A major challenge in developmental biology is unraveling the precise regulation of plant stem cell maintenance and the transition to a fully differentiated cell. In this review, we highlight major themes coordinating the acquisition of cell identity and subsequent differentiation...
作者:John McCullough , Adam Frost , Wesley I. Sundquist
来源:[J].Annual Review of Cell and Developmental Biology(IF 17.983), 2018, Vol.34, pp.85-109Annual Reviews
摘要:The endosomal sorting complexes required for transport (ESCRT) pathway mediates cellular membrane remodeling and fission reactions. The pathway comprises five core complexes: ALIX, ESCRT-I, ESCRT-II, ESCRT-III, and Vps4. These soluble complexes are typically recruited to target m...
作者:Leif Oxburgh
来源:[J].Annual Review of Cell and Developmental Biology(IF 17.983), 2018, Vol.34, pp.427-450Annual Reviews
摘要:The nephron is a multifunctional filtration device equipped with an array of sophisticated sensors. For appropriate physiological function in the human and mouse, nephrons must be stereotypically arrayed in large numbers, and this essential structural property that defines the ki...

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