全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Malvina Hoxha , G. Enrico Rovati , Aurora Bueno Cavanillas
来源:[J].European Journal of Clinical Pharmacology(IF 2.741), 2017, Vol.73 (7), pp.799-809Springer
摘要:... In the late 1990s, leukotriene receptor antagonists (LTRAs) were introduced in therapy for asthma and later on, approved for the relief of the symptoms of allergic rhinitis, chronic obstructive pulmonary disease, and urticaria. In addition, it has been shown that LTRAs may ha...
作者:Montella Silvia , Maglione Marco , De Stefano Sara ...
来源:[J].Italian Journal of Pediatrics(IF 1.344), 2012, Vol.38 (1)DOAJ
摘要:... Since Leukotrienes (LTs) are chemical mediators of airway inflammation in asthma, the leukotriene receptor antagonists (LTRAs) are traditionally used as potent anti-inflammatory drugs in the long-term treatment of asthma in adults, adolescents, and school-age children. In par...
作者:Andrew M Wilson , Paul M O'Byrne , Krishnan Parameswaran
来源:[J].The American Journal of Medicine(IF 4.768), 2003, Vol.116 (5), pp.338-344Elsevier
摘要:Abstract(#br)Purpose(#br)To compare the clinical efficacy of leukotriene receptor antagonists with that of placebo, antihistamines, and nasal corticosteroids in patients with allergic rhinitis or nasal polyposis.(#br)Methods(#br)We performed a systematic review and meta-analysis ...
作者:Chang-Hung Kuo , San-Nan Yang , Hsuan-Fu Kuo ...
来源:[J].Pulmonary Pharmacology & Therapeutics(IF 2.543), 2016, Vol.39, pp.28-37Elsevier
摘要:Abstract(#br)Background(#br)Cysteinyl leukotriene receptor antagonists are important controllers in treating asthma. Human myeloid DCs (mDCs) play critical roles in the pathogenesis of asthma. However, the effects of cysteinyl leukotriene receptor antagonist on human mDCs are u...
作者:Tae-Sun Ha , Ja Ae Nam , Su-Bin Seong ...
来源:[J].Inflammation Research(IF 1.964), 2017, Vol.66 (9), pp.793-802Springer
摘要:Interleukin-13 (IL-13) has recently been reported to be a potential cytokine in the pathogenesis of minimal-change nephrotic syndrome (MCNS). However, the mechanistic insights associated with podocyte dysfunction mediated by IL-13-induced changes in various slit diaphragm (SD) an...
作者:Moises Garcia , Toshihiro Nakabayashi , Erito Mochiki ...
来源:[J].Digestive Diseases and Sciences(IF 2.26), 2004, Vol.49 (7-8), pp.1228-1235Springer
摘要:Abstract(#br)Current information on the effects of leukotriene receptor antagonists on gastrointestinal motility and their mechanisms of gastrointestinal side effects are unknown. Our study aimed to answer the question whether the leukotriene inhibition induced by Pranlukast a...
作者:Mohsen Sadatsafavi , Larry Lynd , Carlo Marra ...
来源:[J].The Journal of Allergy and Clinical Immunology(IF 12.047), 2013, Vol.132 (1), pp.63-69Elsevier
摘要:Background(#br)Recent evidence suggests that the use of leukotriene receptor antagonists (LTRAs) in addition to inhaled corticosteroids (ICSs) in asthmatic patients provides comparable benefits to the addition of long-acting β-agonists (LABAs) to ICSs.(#br)Objective(#br)We soug...
作者:Hiroyuki Fujiwara , Ryo Konno , Sachiho Netsu ...
来源:[J].European Journal of Obstetrics and Gynecology(IF 1.843), 2009, Vol.148 (2), pp.195-198Elsevier
摘要:Abstract(#br)Objective(#br)To investigate the effectiveness of montelukast, a leukotriene receptor antagonist, in alleviating the symptoms of dysmenorrhea.(#br)Study design(#br)This prospective, double-blind, randomized, placebo-controlled study was comprised of 62 patients with...
作者:PHILIPPE DEVILLIER , NATHALIE BACCARD , CHARLES ADVENIER
来源:[J].Pharmacological Research(IF 4.346), 1999, Vol.40 (1), pp.15-29Elsevier
摘要:... Two main classes of leukotriene modulators have been developed: CysLT 1 receptor antagonists and leukotriene synthesis inhibitors. This article reviews the pharmacodynamics, the effects on baseline airway function, the protective effects in airway challenges as well as the re...
作者:Androniki Bili , John J. Condemi , Susan M. Bottone ...
来源:[J].The Journal of Allergy and Clinical Immunology(IF 12.047), 1999, Vol.104 (5), pp.1060-1065Elsevier
摘要:Abstract(#br)Background: Various forms of Churg-Strauss syndrome have been reported in association with the use of leukotriene receptor antagonists in asthmatic patients. Objective: Our purpose was to increase awareness that different forms of the Churg-Strauss syndrome occur in ...

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