全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Xiufeng Tang , Honglei Nian , Xiaoxi Li ...
来源:[J].BMC Complementary and Alternative Medicine(IF 2.082), 2017, Vol.17 (1)Springer
摘要:Asthma is characterized by chronic airway inflammation, leading to structura1 changes in the airway, collectively termed airway remodeling. Airway remodeling is thought to contribute to airway hyper responsiveness and irreversible airflow limitation. The combination of Herba Epim...
作者:Dejan Radovanovic , Pierachille Santus , Francesco Blasi ...
来源:[J].Multidisciplinary Respiratory Medicine(IF 0.151), 2017, Vol.12 (1)Springer
摘要:... In view of the numerous ancillary effects acting on inflammation, airway remodeling, mucus production and cough reflex, along with the good safety profile and the broad spectrum of efficacy demonstrated in different disease phenotypes, tiotropium can represent a beneficial al...
作者:Markus Fehrholz , Kirsten Glaser , Christian P. Speer ...
来源:[J].Respiratory Research(IF 3.642), 2017, Vol.18 (1)Springer
摘要:... While anti-inflammatory effects of glucocorticoids are well defined, their impact on airway remodeling is less characterized. Caffeine has been ascribed to positive effects on airway inflammation as well as remodeling. Connective tissue growth factor (CTGF, CCN2) plays a key ...
作者:Zhimei Yang , Jianguo Zhuang , Lei Zhao ...
来源:[J].Respiratory Research(IF 3.642), 2017, Vol.18 (1)Springer
摘要:Asthma is characterized by chronic airway inflammation, airway hyperresponsiveness (AHR), and airway remodeling. While exposure of house dust mites (HDM) is a common cause of asthma, the pathogenesis of the HDM-induced asthma is not fully understood. Bronchopulmonary C-fibers (PC...
作者:Na Wang , Di Yan , Yi Liu ...
来源:[J].Respiratory Research(IF 3.642), 2016, Vol.17 (1)Springer
摘要:... For years, asthma-associated airway injury remains elusive. Transforming growth factor β1 (TGF-β1) is a pleiotropic cytokine that has been shown to be involved in the synthesis of the matrix molecules associated with airway remodeling. Human antigen R (HuR), the member...
作者:Fabio Stellari , Angelo Sala , Francesca Ruscitti ...
来源:[J].Journal of Translational Medicine(IF 3.459), 2015, Vol.13 (1)Springer
摘要:... A major drawback of these models is represented by the transient nature of the airway pathology peaking 24–72 h after challenge and resolving in 1–2 weeks. We characterized the temporal evolution of pulmonary inflammation and tissue remodeling in a recently described ...
作者:Qixiao Liu , Haijun Li , Qin Wang ...
来源:[J].Respiratory Research(IF 3.642), 2016, Vol.17 (1)Springer
摘要:Abstract(#br) Background(#br)The airway epithelium of chronic obstructive pulmonary disease (COPD) patients undergoes aberrant repair and remodeling after repetitive injury following exposure to environmental factors. Abnormal airway regeneration observed in COPD is thought to ...
作者:Maha M. Abdel-Fattah , Abeer A.A. Salama , Basim A. Shehata ...
来源:[J].Pharmacological Reports(IF 1.965), 2015, Vol.67 (5), pp.943-951Elsevier
摘要:... Angiotensin II is now accused to be potentially implicated in its pathogenesis, being a potent pro-inflammatory mediator with remodeling effects.(#br)Objective(#br)This study aims to evaluate the possible protective effect of telmisartan, an angiotensin II receptor block...
作者:Mohammad Afzal Khan , Abdullah Mohammed Assiri , Dieter Clemens Broering
来源:[J].Journal of Translational Medicine(IF 3.459), 2015, Vol.13 (1)Springer
摘要:... Complement mediators that accelerate the airway remodeling are not well defined; however, an uncontrolled Th2-driven adaptive immune response has been linked to the major pathophysiologic features of asthma, including bronchoconstriction, airway hyperresponsiveness, and airway...
作者:Ming-Wei Chang , Chung-Ru Lee , Hsueh-Fen Hung ...
来源:[J].International Journal of Environmental Research and Public Health(IF 1.998), 2013, Vol.11 (1), pp.337-354DOAJ
摘要:The composting procedure in food waste plants generates airborne bioaerosols that have the potential to damage human airway epithelial cells. Persistent inflammation and repair responses induce airway remodeling and damage to the respiratory system. This study elucidated the ...

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