全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Hyungtaek Jeon , Ji-Su Lee , Seungmin Yoo ...
来源:[J].Journal of Immunological Methods(IF 2.225), 2014, Vol.415, pp.57-62Elsevier
摘要:Abstract(#br)The complement system is an important aspect of immune defense against microbial invasion. Eukaryotic cells express various complement regulatory proteins to protect them from uncontrolled complement activation. However, some eukaryotic cells possess constitutive complement system...
作者:Yan Lv , Cao Chen , Bao-Yun Zhang ...
来源:[J].Molecular Neurobiology(IF 5.471), 2015, Vol.52 (3), pp.1165-1179Springer
摘要:Abstract(#br)As an integral part of the innate immunity, the complement system has been reported to involve in the pathogenesis of prion diseases (PrD). However, the states of expression and activity of complement proteins in experimental models of scrapie infection are still not...
作者:Anas H. Abu-Humaidan , Malin Elvén , Andreas Sonesson ...
来源:[J].Frontiers in Immunology, 2018, Vol.9DOAJ
摘要:The complement system is an ancient part of the innate immune system important for both tissue homeostasis and host defense. However, bacteria like Staphylococcus aureus (SA) possess elaborative mechanisms for evading both the complement system and other parts of the immune system...
作者:Zsófia Horváth , Dorottya Csuka , Katarina Vargova ...
来源:[J].Molecular Immunology(IF 2.645), 2013, Vol.54 (1), pp.8-13Elsevier
摘要:Abstract(#br)Clinical studies as well as animal models emphasized the importance of the complement system in the pathogenesis of coronary atherosclerosis and cardiovascular diseases. Our aim was to examine the extent and clinical implication of complement system activation in p...
作者:Finn Sellebjerg , Irakli Jaliashvili , Michael Christiansen ...
来源:[J].Journal of the Neurological Sciences(IF 2.243), 1998, Vol.157 (2), pp.168-174Elsevier
摘要:Abstract(#br)Background: The pathogenesis of multiple sclerosis (MS) appears to involve autoimmune phenomena in the central nervous system. Activation of the complement system is suggested to be involved in the pathogenesis. Patients and methods: Cerebrospinal fluid (CSF) and pla...
作者:Zoltán Derzsy , Zoltán Prohászka , János Rigó ...
来源:[J].Molecular Immunology(IF 2.645), 2010, Vol.47 (7), pp.1500-1506Elsevier
摘要:Abstract(#br)The purpose of this study was to explore the role of the complement system in normal human pregnancy and preeclampsia in a comprehensive manner, measuring circulating levels of complement proteins, their activation fragments and regulatory factors, as well as those o...
作者:Yo-ichi Ishida , Kiyoshi Yamashita , Hidenori Sasaki ...
来源:[J].Cancer Letters(IF 4.258), 2008, Vol.271 (1), pp.167-177Elsevier
摘要:... MS/MS ion search using tandem mass spectrometry and immunoprecipitation assay using anti-C3 antibody showed that factors derived from these candidate peaks were identified as C3f, which is a component of the complement system and a fragment of complement C3. These results ind...
作者:Friederike Hecke , Thomas Hoehn , Evelyn Strauss ...
来源:[J].Mediators of Inflammation(IF 3.882), 2001, Vol.10 (1)Hindawi
摘要:Introduction : Complement activation occurs secondary to a variety of external stimuli. Lactic acidosis has been previously shown to activate the complement factors C3a and C5a. In the present investigation we examined the differential effect of lactic acidosis on anaphylatox...
作者:Ya-ping Gao , Jie Dong , Xin Zhang ...
来源:[J].Cell Biochemistry and Biophysics(IF 1.912), 2013, Vol.66 (3), pp.753-757Springer
摘要:... In the further investigation, it was found the synthesized peptide EC1 (154–165aa of Efb) could specifically bind C3/C3b and subsequently to block the activation of complement. Meanwhile, EC1 could inhibit the interaction between Efb and C3/C3b. Moreover, the interactio...
作者:Luigi Bergamaschini , Cesare Donarini , Giulia Gobbo ...
来源:[J].Mechanisms of Ageing and Development(IF 3.264), 2001, Vol.122 (16), pp.1971-1983Elsevier
摘要:... Non-fibrillar βA1-42, and truncated peptide 1–28, induced dose-dependent activation of C4 sparing C3. The mechanism of C4 activation was not dependent on C1q, because non-fibrillar βA can still activate C4 in plasma genetically deficient in C1q. A C1q independent mec...

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