全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Qi Wu , Yadi Wang , Yun Ding ...
来源:[J].Science China Life Sciences(IF 2.024), 2017, Vol.60 (4), pp.432-435Springer
作者:Naeh L. Klages-Mundt , Lei Li
来源:[J].Science China Life Sciences(IF 2.024), 2017, Vol.60 (10), pp.1065-1076Springer
摘要:DNA is constantly exposed to a wide array of genotoxic agents, generating a variety of forms of DNA damage. DNA-protein crosslinks (DPCs)—the covalent linkage of proteins with a DNA strand—are one of the most deleterious and understudied forms of DNA damage, posing as steric...
来源:[J].Science China Life Sciences(IF 2.024), 2017, Vol.60 (4), pp.345-347Springer
作者:Guangdun Peng , Naihe Jing
来源:[J].Science China Life Sciences(IF 2.024), 2017, Vol.60 (4), pp.363-369Springer
摘要:The diverse morphologies among vertebrate species stems from the evolution of a basic body plan that is constituted by a spatially organized ensemble of tissue lineage progenitors. At gastrulation, this body plan is established through a coordinated morphogenetic process and the ...
作者:Arthur S. Levine , Margaret C. McDonald , Charles E. Bogosta
来源:[J].Science China Life Sciences(IF 2.024), 2017, Vol.60 (10), pp.1150-1156Springer
摘要:In 2011, the University of Pittsburgh School of Medicine (UPSOM) and Tsinghua University formed a partnership to further the education of Tsinghua medical students. These students come to UPSOM as visiting research scholars for two years of their eight-year MD curriculum. Du...
作者:Arthur S. Levine , Luxi Sun , Rong Tan ...
来源:[J].Science China Life Sciences(IF 2.024), 2017, Vol.60 (10), pp.1077-1080Springer
摘要:Endogenous stress and exogenous toxicants (chemicals and UV light) alter genetic information either directly or indirectly through the production of reactive oxygen species (ROS), thereby driving genomic instability in cells and promoting tumorigenesis. All living cells try to fa...
作者:Fang Lv , Xiaonan Cong , Wenshu Tang ...
来源:[J].Science China Life Sciences(IF 2.024), 2017, Vol.60 (4), pp.397-403Springer
摘要:Hemostasis is a major challenge in surgical procedures and traumas. Conventional hemostatic methods have limited efficacy and may cause additional tissue damage. In this study, we designed a novel hemostatic agent based on the in situ gel formation of gelatin cross-linked by...
作者:Liang Wang , Lei Liu , Lingsong Qin ...
来源:[J].Science China Life Sciences(IF 2.024), 2017, Vol.60 (4), pp.333-344Springer
摘要:Reticulophagy is a type of selective autophagy in which protein aggregate-containing and/or damaged endoplasmic reticulum (ER) fragments are engulfed for lysosomal degradation, which is important for ER homeostasis. Several chemical drugs and mutant proteins that promote protein ...

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