全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Leen Vijgen , Kim Thys , An Vandebosch ...
来源:[J].Virology Journal(IF 2.092), 2017, Vol.14 (1)Springer
摘要:In study TMC647055HPC2001, a 3-direct-acting-antiviral (DAA) regimen combining NS3/4A protease inhibitor simeprevir (SMV), non-nucleoside NS5B inhibitor TMC647055/ritonavir (RTV) and NS5A inhibitor JNJ-56914845 resulted in high sustained virologic response 12 weeks after actual e...
作者:Boxiang Gui , Qin Chen , Chuanxia Hu ...
来源:[J].Virology Journal(IF 2.092), 2017, Vol.14 (1)Springer
摘要:H9N2 influenza viruses circulate globally and are considered to have pandemic potential. The hyper-inflammatory response elicited by these viruses is thought to contribute to disease severity. Calcitriol plays an important role in modulating the immune response to viral infection...
作者:Ye Zhang , Wei-Lu Zhang , Xiao-Wen Pang ...
来源:[J].Virology Journal(IF 2.092), 2017, Vol.14 (1)Springer
摘要:Controversy remains as to whether antiviral agents contribute to renal dysfunction in patients with chronic hepatitis B virus (HBV) infection. Thus, the aim of study was to analyze the changes in renal function of chronic hepatitis B (CHB) patients in response to anti-HBV therapy...
作者:Ha-Hyun Kim , Dong-Kun Yang , Jin-Ju Nah ...
来源:[J].Virology Journal(IF 2.092), 2017, Vol.14 (1)Springer
摘要:Rabies is an important viral zoonosis that causes acute encephalitis and death in mammals. To date, several recombinant vaccines have been developed based on G protein, which is considered to be the main antigen, and these vaccines are used for rabies control in many countries. M...
作者:Chunfu Zheng , Chenhe Su
来源:[J].Virology Journal(IF 2.092), 2017, Vol.14 (1)Springer
摘要:Herpes simplex virus 1 (HSV-1) is an archetypal member of the alphaherpesvirus subfamily with a large genome encoding over 80 proteins, many of which play a critical role in virus-host interactions and immune modulation. Upon viral infections, the host cells activate innate immun...
作者:Yuzhen Zhang , Bram Vrancken , Yun Feng ...
来源:[J].Virology Journal(IF 2.092), 2017, Vol.14 (1)Springer
摘要:Rabies is an important but underestimated threat to public health, with most cases reported in Asia. Since 2000, a new epidemic wave of rabies has emerged in Yunnan Province, southwestern China, which borders three countries in Southeast Asia.
作者:Yijian Wu , Longping Cui , Erpeng Zhu ...
来源:[J].Virology Journal(IF 2.092), 2017, Vol.14 (1)Springer
摘要:Muscovy duck reovirus (MDRV) causes high morbidity and mortality in Muscovy ducklings at 10 days old and can persist in an infected flock until the ducklings of 6 weeks old. It shares common physicochemical properties with avian reovirus (ARV) and differs in coding assignment and...
作者:Mamneet Manghera , Alycia Magnusson , Renée N. Douville
来源:[J].Virology Journal(IF 2.092), 2017, Vol.14 (1)Springer
摘要:Retroviruses are known to rely extensively on the expression of viral proteins from the sense proviral genomic strand. Yet, the production of regulatory retroviral proteins from antisense-encoded viral genes is gaining research attention, due to their clinical significance. This ...
作者:Elena A. Tyschik , Sophia M. Shcherbakova , Ruslan R. Ibragimov ...
来源:[J].Virology Journal(IF 2.092), 2017, Vol.14 (1)Springer
摘要:TTV has been detected in almost every human tissue type or body fluid reaching near 100% prevalence. Several studies report mother-to-child postnatal transmission of TTV in infancy but the risk of transplacental transmission of TTV is still unclear.
作者:Karolin Meixenberger , Kaveh Pouran Yousef , Maureen Rebecca Smith ...
来源:[J].Virology Journal(IF 2.092), 2017, Vol.14 (1)Springer
摘要:Detailed knowledge of the evolutionary potential of polymorphic sites in a viral protein is important for understanding the development of drug resistance in the presence of an inhibitor. We therefore set out to analyse the molecular evolution of the HIV-1 subtype B integrase at ...

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