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作者:Shigehiko Ogoh
来源:[J].The Journal of Physiological Sciences(IF 1.089), 2017, Vol.67 (3), pp.345-351
摘要:Ageing is the primary risk factor for cognitive deterioration. Given that the cerebral blood flow (CBF) or regulation of cerebral circulation is attenuated in the elderly, it could be expected that ageing-induced cognitive deterioration may be affected by a decrease in CBF as a r...
作者:Yuka Okusha , Yoshiyuki Hirai , Hitoshi Maezawa ...
来源:[J].The Journal of Physiological Sciences(IF 1.089), 2017, Vol.67 (4), pp.467-474
摘要:To evaluate relative factors for anorectic effects of l -histidine, we performed behavioral experiments for measuring food and fluid intake, conditioned taste aversion (CTA), taste disturbance, and c-Fos immunoreactive (Fos-ir) cells before and after i.p. injection with l -histid...
作者:Senay Akin , Hisashi Naito , Yuji Ogura ...
来源:[J].The Journal of Physiological Sciences(IF 1.089), 2017, Vol.67 (3), pp.407-413
摘要:Heat shock proteins (Hsps) have a critical role in maintaining cellular homeostasis and in protecting cells from a range of acute and chronic stressful conditions. Treadmill running exercise results in increased Hsp72 and Hsp25 levels in various tissues and heat production d...
作者:İlknur Birsen , Burcu Gemici , Nuray Acar ...
来源:[J].The Journal of Physiological Sciences(IF 1.089), 2017, Vol.67 (3), pp.373-385
摘要:The objective of this study was to explore the role of apelin in the healing of gastric lesions induced by stress. Male Wistar rats were exposed to water immersion and restraint stress (WIRS) for 6 h with or without the apelin receptor antagonist F13A. The rats were killed o...
作者:Kayoko Oda , Masanari Umemura , Rina Nakakaji ...
来源:[J].The Journal of Physiological Sciences(IF 1.089), 2017, Vol.67 (4), pp.497-505
摘要:Melanoma has an extremely poor prognosis due to its rapidly progressive and highly metastatic nature. Several therapeutic drugs have recently become available, but are effective only against melanoma with specific BRAF gene mutation. Thus, there is a need to identify other target...
作者:Takuro Tobina , Yukari Mori , Yukiko Doi ...
来源:[J].The Journal of Physiological Sciences(IF 1.089), 2017, Vol.67 (5), pp.595-602
摘要:Muscle peroxisome proliferator-activated receptor gamma co-activator 1 (PGC-1)α gene expression is influenced by the Gly482Ser gene polymorphism, which is a candidate genetic risk factor for diabetes mellitus and obesity. This study investigated the effects of PGC-1 gene Gly...
作者:Fereshteh Safari , Shahnaz Shekarforoosh , Tahmineh Hashemi ...
来源:[J].The Journal of Physiological Sciences(IF 1.089), 2017, Vol.67 (4), pp.515-522
摘要:The aim of this study was to investigate the effect of sirtinol, as an inhibitor of sirtuin NAD-dependent histone deacetylases, on myocardial ischemia reperfusion injury following early and late ischemia preconditioning (IPC). Rats underwent sustained ischemia and reperfusion (IR...
作者:Kenichi Sasaguri , Kentaro Yamada , Yuri Narimatsu ...
来源:[J].The Journal of Physiological Sciences(IF 1.089), 2017, Vol.67 (4), pp.489-496
摘要:Galectin-1 (Gal-1) is differentially expressed in normal and pathological tissues and regulates immune cell homeostasis. Restraint stress increases serum Gal-1 in rats. However, the function of stress-induced Gal-1 in serum is unknown. We determined if stress-induced Gal-1 i...
作者:Kenji Sunagawa
来源:[J].The Journal of Physiological Sciences(IF 1.089), 2017, Vol.67 (4), pp.447-458
摘要:Guyton’s most significant contributions are the exploration into the development of venous return and circulatory equilibrium. Recently, several physiologists challenged the validity of venous return as a function of venous pressure. Guyton’s experiment in effect controlled ...
作者:Jiao Lu , Shan-Shan Pan
来源:[J].The Journal of Physiological Sciences(IF 1.089), 2017, Vol.67 (4), pp.475-487
摘要:To evaluate exercise preconditioning (EP)-induced cardioprotective effects against exercise-induced acute myocardial injury and investigate the alterations of C-type natriuretic peptide (CNP) and its specific receptor, natriuretic peptide receptor B (NPR-B), during EP-induced car...

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