全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Toumazou Chris , Cass Tony
来源:[J].PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES(IF 6.23), 2007, Vol.362 (1484), pp.1321-8PubMed
摘要:The accurate monitoring of the physiological status of cells, tissues and whole organisms demands a new generation of devices capable of providing accurate data in real time with minimal perturbation of the system being measured. To deliver on the promise of cell-bionics advances...
作者:Brodin Anders
来源:[J].PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES(IF 6.23), 2007, Vol.362 (1486), pp.1857-71PubMed
摘要:Many small passerines are resident in forests with very cold winters. Considering their size and the adverse conditions, this is a remarkable feat that requires optimal energy management in several respects, for example regulation of body fat reserves, food hoarding and night-tim...
作者:Krüger Oliver
来源:[J].PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES(IF 6.23), 2007, Vol.362 (1486), pp.1873-86PubMed
摘要:The interactions between brood parasitic birds and their host species provide one of the best model systems for coevolution. Despite being intensively studied, the parasite-host system provides ample opportunities to test new predictions from both coevolutionary theory as well as...
作者:Eisenberg David , Marcotte Edward , McLachlan Andrew D ...
来源:[J].PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES(IF 6.23), 2006, Vol.361 (1467), pp.525-7PubMed
摘要:The science of bioinformatics has developed in the wake of methods to determine the sequences of the informational macromolecules--DNAs, RNAs and proteins. But in a wider sense, the biological world depends in its every process on the transmission of information, and hence bioinf...
作者:Foerstner Konrad U , von Mering Christian , Bork Peer
来源:[J].PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES(IF 6.23), 2006, Vol.361 (1467), pp.519-23PubMed
摘要:Environmental sequencing, also dubbed metagenomics, is increasingly being used to obtain insights into organismal communities in diverse habitats, and has a variety of potential applications foreseeable in biotechnology and medicine. The first public large-scale data provide alre...
作者:Pereira-Leal Jose B , Levy Emmanuel D , Teichmann Sarah A
来源:[J].PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES(IF 6.23), 2006, Vol.361 (1467), pp.507-17PubMed
摘要:Modularity is an attribute of a system that can be decomposed into a set of cohesive entities that are loosely coupled. Many cellular networks can be decomposed into functional modules-each functionally separable from the other modules. The protein complexes in physical protein i...
作者:Ramsey S , Ozinsky A , Clark A ...
来源:[J].PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES(IF 6.23), 2006, Vol.361 (1467), pp.495-506PubMed
摘要:Transcriptional noise is known to play a crucial role in heterogeneity in bacteria and yeast. Mammalian macrophages are known to exhibit cell-to-cell variation in their responses to pathogens, but the source of this heterogeneity is not known. We have developed a detailed stochas...
作者:Schlitt Thomas , Brazma Alvis
来源:[J].PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES(IF 6.23), 2006, Vol.361 (1467), pp.483-94PubMed
摘要:Approaches to describe gene regulation networks can be categorized by increasing detail, as network parts lists, network topology models, network control logic models or dynamic models. We discuss the current state of the art for each of these approaches. We study the relationshi...
作者:Oliver Stephen G
来源:[J].PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES(IF 6.23), 2006, Vol.361 (1467), pp.477-82PubMed
摘要:Metabolic Control Analysis (MCA) is a conceptual and mathematical formalism that models the relative contributions of individual effectors in a pathway to both the flux through the pathway and the concentrations of individual intermediates within it. To exploit MCA in an initial ...
作者:Hurwitz Naama , Pellegrini-Calace Marialuisa , Jones David T
来源:[J].PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES(IF 6.23), 2006, Vol.361 (1467), pp.465-75PubMed
摘要:In this paper we briefly review some of the recent progress made by ourselves and others in developing methods for predicting the structures of transmembrane proteins from amino acid sequence. Transmembrane proteins are an important class of proteins involved in many diverse biol...

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