全部文献期刊会议图书|学者科研项目
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作者:Pegah Dejban , Nastaran Rahimi , Nasrin Takzare ...
来源:[J].Pharmacological Reports(IF 1.965), 2020, Vol.72 (1), pp.135-146
摘要:Abstract(#br)Background(#br)Inflammatory bowel disease is an intestinal disorder presented by recurrent inflammation in the gastrointestinal tract. It has been reported that modafinil, also known as an awakening drug, has anti-inflammatory characteristics. The objective of t...
作者:Nuriye Ezgi Bektur Aykanat , Sedat Kacar , Serife Karakaya ...
来源:[J].Pharmacological Reports(IF 1.965), 2020, Vol.72 (1327–41), pp.199-207
摘要:Abstract(#br)Background(#br)14 million people are diagnosed with new cancer and approximately 8 million people die from cancer every year. Hepatocellular carcinoma is the most common type of liver cancer and covers almost 5–6% of cancer deaths worldwide. Silybum marianum, a ...
作者:Julia Zaccarelli-Magalhães , André Rinaldi Fukushima , Natalia Moreira ...
来源:[J].Pharmacological Reports(IF 1.965), 2020, Vol.72 (1), pp.24-35
摘要:Abstract(#br)Background(#br)Depression is one of the most common mentally debilitating diseases in the world. Ketamine has been recently identified as a potential novel antidepressant. Further animal model evaluations of the use of ketamine as an antidepressant are necessary to d...
作者:Ilona Nowak-Kózka , Kamil J. Polok , Jacek Górka ...
来源:[J].Pharmacological Reports(IF 1.965), 2020, Vol.72 (1), pp.147-155
摘要:Abstract(#br)Background(#br)The effect of renal replacement therapy on drug concentrations in patients with sepsis has not been fully elucidated because the pharmacokinetic properties of many antimicrobials are influenced by both pathophysiological and treatment-related fact...
作者:Ewa Toton , Izabela Kedziora , Aleksandra Romaniuk-Drapala ...
来源:[J].Pharmacological Reports(IF 1.965), 2020, Vol.72 (3), pp.166-178
摘要:Abstract(#br)Background(#br)Drosera spatulata is a source of many compounds such as naphthoquinones, phenolic acids, flavonoids, anthocyanins, and naphthalene derivatives. Unfortunately, the information regarding the biological activity and chemical profile of those compounds is ...
作者:Daniela H. Oliveira , Fernanda S. S. Sousa , Paloma T. Birmann ...
来源:[J].Pharmacological Reports(IF 1.965), 2020, Vol.72 (1), pp.36-46
摘要:Abstract(#br)Background/objectives(#br)4-(Arylchalcogenyl)-1 H -pyrazoles containing selenium or sulfur (0.001–50 mg/kg) were investigated regarding the intragastric route effect ( ig ) administration on nociception in mice. In this study, nociception and inflammation were i...
作者:Jarogniew J. Łuszczki , Jacek Lepiech , Mirosław Zagaja ...
来源:[J].Pharmacological Reports(IF 1.965), 2020, Vol.72 (10), pp.87-95
摘要:Abstract(#br)Background(#br)Anticonvulsant and acute toxic effects of 5-[(3-fluorophenyl)ethyl]-4-( n -hexyl)-2,4-dihydro-3 H -1,2,4-triazole-3-thione (TPF-34)—a candidate for novel antiepileptic drug—were examined in the maximal electroshock-induced seizure (MES) model and ...
作者:Kristýna Nosková , Gabriela Dovrtělová , Ondřej Zendulka ...
来源:[J].Pharmacological Reports(IF 1.965), 2020, Vol.72 (8), pp.156-165
摘要:Abstract(#br)Background(#br)Lycopene as a naturally occurring carotenoid is a common part of the human diet. Several beneficial properties of lycopene have been identified, with the most studied being anti-cancer and antioxidant activity. However, no evidence of possible dru...
作者:Siyuan Liu , Lu Wang , Wangwang Ding ...
来源:[J].Pharmacological Reports(IF 1.965), 2020, Vol.72 (1), pp.188-198
摘要:Abstract(#br)Background(#br)Cleistanthin A (CleA), a natural diphyllin glycoside, has been shown to suppress the invasion of cancer cells, but the underlying mechanisms remain unclear. Here, the inhibitory effect of CleA on the invasion of MDA-MB-231 human breast cancer cell...
作者:Megan McGrath , Mansi Tolia , Douglas E. Raines
来源:[J].Pharmacological Reports(IF 1.965), 2020, Vol.72 (1), pp.260-266
摘要:Abstract(#br)Background(#br)Many sedative-hypnotic agents are thought to act by positively modulating γ-aminobutyric acid type A (GABAA) receptors. However, for many agents, the location(s) of the binding site(s) responsible for such receptor modulation is uncerta...

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