全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Thuy Vu , Peiming Ma , Jiyun Sunny Chen ...
来源:[J].Pharmaceutical Research(IF 4.742), 2017, Vol.34 (9), pp.1784-1795Springer
摘要:Capsaicin-induced dermal blood flow (CIDBF) is a validated biomarker used to evaluate the target engagement of potential calcitonin gene-related peptide-blocking therapeutics for migraine. To characterize the pharmacokinetics (PK) and quantify the inhibitory effects of erenumab (...
作者:Jiaqi Yu , Jennifer Wong , Ari Ukkonen ...
来源:[J].Pharmaceutical Research(IF 4.742), 2017, Vol.34 (8), pp.1707-1715Springer
摘要:This work investigated the effect of relative humidity (RH) on bipolar electrostatic charge profiles of dry powder inhaler aerosols using the Bipolar Charge Analyzer (BOLAR).
作者:Kaushalkumar Dave , Fahd M. Alsharif , Saiful Islam ...
来源:[J].Pharmaceutical Research(IF 4.742), 2017, Vol.34 (9), pp.1897-1907Springer
摘要:Almost all breast cancers originate from epithelial cells lining the milk ducts in the breast. To this end, the study investigated the feasibility of localized transdermal delivery of α-santalol, a natural chemopreventive agent to the breast.
作者:Byeongtaek Oh , Yugyung Lee , Mingui Fu ...
来源:[J].Pharmaceutical Research(IF 4.742), 2017, Vol.34 (10), pp.2066-2074Springer
摘要:Thiolated-graphene quantum dots (SH-GQDs) were developed and assessed for an efficient preventive means against atherosclerosis and potential toxicity through computational image analysis and animal model studies.
作者:Christopher J. Morris , Ghaith Aljayyoussi , Omar Mansour ...
来源:[J].Pharmaceutical Research(IF 4.742), 2017, Vol.34 (12), pp.2517-2531Springer
摘要:Polyamidoamine (PAMAM) dendrimers are a promising class of nanocarrier with applications in both small and large molecule drug delivery. Here we report a comprehensive evaluation of the uptake and transport pathways that contribute to the lung disposition of dendrimers.
作者:Baochun Yang , Mei Shen , Jianqiang Liu ...
来源:[J].Pharmaceutical Research(IF 4.742), 2017, Vol.34 (11), pp.2440-2450Springer
摘要:Metal-organic frameworks (MOFs) have shown great potentials as drug delivery carriers, but the conventional methods for MOFs synthesis limited their use in biomedicine. The aim of this study was engineered tumor-targeted zinc nanoscale MOFs encapsulating chemotherapy drug.
作者:Deepanshu Shilpi , Varun Kushwah , Ashish Kumar Agrawal ...
来源:[J].Pharmaceutical Research(IF 4.742), 2017, Vol.34 (7), pp.1505-1516Springer
摘要:The present study evaluates the effects of stearic acid conjugation with gelatin and, its pharmaceutical potential to formulate novel atorvastatin (AT) loaded nanoparticles.
作者:Suellen M. T. Cavalcanti , Cláudia Nunes , Sofia A. C. Lima ...
来源:[J].Pharmaceutical Research(IF 4.742), 2017, Vol.34 (6), pp.1204-1216Springer
摘要:An optimized methodology for the development of a new generation of lipid nanoparticles, the multiple lipid nanoparticles (MLN) is described. MLN have characteristics between nanostructured lipid carriers (NLC) and multiple emulsions (W/O/W), but without the outer aqueous phase.
作者:Urszula Cibor , Małgorzata Krok-Borkowicz , Monika Brzychczy-Włoch ...
来源:[J].Pharmaceutical Research(IF 4.742), 2017, Vol.34 (10), pp.2075-2083Springer
摘要:To develop polysaccharide-based membranes that allow controlled and localized delivery of gentamicin for the treatment of post-operative bone infections.
作者:Qian Zhang , Michael Murawsky , Terri LaCount ...
来源:[J].Pharmaceutical Research(IF 4.742), 2017, Vol.34 (7), pp.1491-1504Springer
摘要:Performance of a transdermal delivery system (TDS) can be affected by exposure to elevated temperature, which can lead to unintended safety issues. This study investigated TDS and skin temperatures and their relationship in vivo , characterized the effective thermal resistance of...

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