全部文献期刊会议图书|学者科研项目
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作者:Hyun Young Kim , Kyeong Seok Kim , Myung Ji Kim ...
来源:[J].Oxidative Medicine and Cellular Longevity(IF 3.393), 2019, Vol.2019
摘要:Osteoporosis is a degenerative metabolic disease caused by an imbalance between osteogenesis and osteoclastogenesis. Increased levels of proinflammatory cytokines combined with decreased estrogen levels, which are commonly seen in postmenopausal women, can lead to overactiva...
作者:May N. Bin Jumah
来源:[J].Oxidative Medicine and Cellular Longevity(IF 3.393), 2019, Vol.2019
摘要:Monolluma quadrangula is a succulent bush traditionally used to treat diabetes and peptic ulcer. The present study aimed to investigate the effect of M. quadrangula hydroethanolic extract on glucose tolerance, insulin sensitivity, glucose metabolizing enzymes, lipid profile, and ...
作者:Sicheng Li , Qiongyuan Hu , Jinjian Huang ...
来源:[J].Oxidative Medicine and Cellular Longevity(IF 3.393), 2019, Vol.2019
摘要:Sepsis is one of the most serious health hazards. Current research suggests that the pathogenesis of sepsis is mediated by both pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). Mitochondria are among the most important organelles in...
作者:Pierluigi Ramadori , Hannah Drescher , Stephanie Erschfeld ...
来源:[J].Oxidative Medicine and Cellular Longevity(IF 3.393), 2017, Vol.2017
摘要:We have recently shown that hepatocyte-specific c-met deficiency accelerates the progression of nonalcoholic steatohepatitis in experimental murine models resulting in augmented production of reactive oxygen species and accelerated development of fibrosis. The aim of this st...
作者:Tomasz Kubrak , Anna Bogucka-Kocka , Łukasz Komsta ...
来源:[J].Oxidative Medicine and Cellular Longevity(IF 3.393), 2017, Vol.2017
摘要:The presence of multidrug resistance (MDR) in tumor cells is considered as the major cause of failure of cancer chemotherapy. The mechanism responsible for the phenomenon of multidrug resistance is explained, among others, as overexpression of membrane transporters primarily from...
作者:Giovanna Lippe , Gabriele Coluccino , Marco Zancani ...
来源:[J].Oxidative Medicine and Cellular Longevity(IF 3.393), 2019, Vol.2019
摘要:The mitochondrial F-ATP synthase is the principal energy-conserving nanomotor of cells that harnesses the proton motive force generated by the respiratory chain to make ATP from ADP and phosphate in a process known as oxidative phosphorylation. In the energy-converting membranes,...
作者:Xuecong Ren , Li Chen , Jing Xie ...
来源:[J].Oxidative Medicine and Cellular Longevity(IF 3.393), 2017, Vol.2017
摘要:Resveratrol is widely known for its antiaging properties and exerts cardiovascular protective effects in different experimental models. The role of resveratrol in regulating mitochondrial functions and dynamics during the cardiac aging process remains poorly understood. In this s...
作者:Xiyun Bian , Jingman Xu , Huanhuan Zhao ...
来源:[J].Oxidative Medicine and Cellular Longevity(IF 3.393), 2019, Vol.2019
摘要:Background. Zinc plays a role in mitophagy and protects cardiomyocytes from ischemia/reperfusion injury. This study is aimed at investigating whether SUMOylation of Drp1 is involved in the protection of zinc ion on cardiac I/R injury. Methods. Mouse hearts were subjected to ...
作者:Maria S. Manola , Eleni N. Tsakiri , Ioannis P. Trougakos
来源:[J].Oxidative Medicine and Cellular Longevity(IF 3.393), 2019, Vol.2019
摘要:Being an assembly of highly sophisticated protein machines, cells depend heavily on proteostatic modules functionality and on adequate supply of energetic molecules for maintaining proteome stability. Yet, our understanding of the adaptations induced by multigenerational pro...
作者:Qiang Su , Xiangwei Lv , Ziliang Ye
来源:[J].Oxidative Medicine and Cellular Longevity(IF 3.393), 2019, Vol.2019
摘要:Background/Aims. Coronary microembolization- (CME-) induced myocardial injury and progressive cardiac dysfunction are mainly caused due to CME-induced myocardial local inflammatory response and myocardial apoptosis. Ligustrazine plays an important protective role in multiple...

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