全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Deepak Gupta , Parveen Kaur , See Leong ...
来源:[J].Marine Drugs(IF 3.978), 2014, Vol.12 (1), pp.115-127MDPI
摘要:Tropical filamentous marine cyanobacteria have emerged as a viable source of novel bioactive natural products for drug discovery and development. In the present study, aplysiatoxin ( 1 ), debromoaplysiatoxin ( 2 ) and anhydrodebromoaplysiatoxin ( 3 ), as well as two new anal...
作者:Ranga Ambati , Siew-Moi Phang , Sarada Ravi ...
来源:[J].Marine Drugs(IF 3.978), 2014, Vol.12 (1), pp.128-152MDPI
摘要:There is currently much interest in biological active compounds derived from natural resources, especially compounds that can efficiently act on molecular targets, which are involved in various diseases. Astaxanthin (3,3′-dihydroxy-β, β′-carotene-4,4′-dione) is a xantho...
作者:Hong-Ye Li , Yang Lu , Jian-Wei Zheng ...
来源:[J].Marine Drugs(IF 3.978), 2014, Vol.12 (1), pp.153-166MDPI
摘要:The role of diatoms as a source of bioactive compounds has been recently explored. Diatom cells store a high amount of fatty acids, especially certain polyunsaturated fatty acids (PUFAs). However, many aspects of diatom metabolism and the production of PUFAs remain unclear. This ...
作者:Hou-Jin Li , Wen-Han Jiang , Wan-Ling Liang ...
来源:[J].Marine Drugs(IF 3.978), 2014, Vol.12 (1), pp.167-175MDPI
摘要:Chondrostereum sp., a marine fungus isolated from a soft coral Sarcophyton tortuosum , can yield hirsutane framework sesquiterpenoids. However, the metabolites profiles vary dramatically with the composition change of the culture media. This fungus was cultured in a liquid m...
作者:Humberto Domínguez , Guillermo Crespín , Adrián Santiago-Benítez ...
来源:[J].Marine Drugs(IF 3.978), 2014, Vol.12 (1), pp.176-192MDPI
摘要:Marine organisms are an increasingly important source of novel metabolites, some of which have already inspired or become new drugs. In addition, many of these molecules show a high degree of novelty from a structural and/or pharmacological point of view. Structure determination ...
作者:Peter Proksch
来源:[J].Marine Drugs(IF 3.978), 2014, Vol.12 (1), pp.193-195MDPI
摘要:China is one of the first countries to use marine materia medica for treating diseases. Ancient books on Chinese herbology, such as Shennong Bencaojing ( Shennong’s Classic of Materia Medica ), Xinxiu Bencao ( Newly Revised Materia Medica ) and Bencao Gangmu ( Compendium of ...
作者:Shuo-Chueh Chen , Yi-Chung Chien , Chun-Hsu Pan ...
来源:[J].Marine Drugs(IF 3.978), 2014, Vol.12 (1), pp.196-213MDPI
摘要:There are many major causes of cancer death, including metastasis of cancer. Dihydroaustrasulfone alcohol, which is isolated from marine coral, has shown antioxidant activity, but has not been reported to have an anti-cancer effect. We first discovered that dihydroaustrasulfone a...
作者:Zengliang Ruan , Guoyan Liu , Beilei Wang ...
来源:[J].Marine Drugs(IF 3.978), 2014, Vol.12 (1), pp.214-231MDPI
摘要:We first identified and characterized a novel peroxiredoxin (Prx), designated as CcPrx4, from the cDNA library of the tentacle of the jellyfish Cyanea capillata . The full-length cDNA sequence of CcPrx4 consisted of 884 nucleotides with an open reading frame encoding a mature pro...
作者:Vitor Pomin
来源:[J].Marine Drugs(IF 3.978), 2014, Vol.12 (1), pp.232-254MDPI
摘要:Fucosylated chondroitin sulfate (FucCS) is a structurally distinct glycosaminoglycan found in sea cucumber species. It has the same backbone composition of alternating 4-linked glucuronic acid and 3-linked N -acetyl galactosamine residues within disaccharide repeating units as re...
作者:David Newman , Gordon Cragg
来源:[J].Marine Drugs(IF 3.978), 2014, Vol.12 (1), pp.255-278MDPI
摘要:The marine habitat has produced a significant number of very potent marine-derived agents that have the potential to inhibit the growth of human tumor cells in vitro and, in a number of cases, in both in vivo murine models and in humans. Although many agents have entered cli...

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