全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Giuseppe Pelosi , Guido Rindi , William D. Travis ...
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2014, Vol.9 (3), pp.273-284Wolters Kluwer
摘要:Classification of lung neuroendocrine (NE) tumors is a step-wise process with four tumor categories being identified by morphology, namely typical carcinoid (TC), atypical carcinoid, large-cell NE carcinoma, and small-cell lung carcinoma (SCLC). Ki-67 antigen or protein (hencefor...
作者:Florian Cabillic , Audrey Gros , Frédéric Dugay ...
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2014, Vol.9 (3), pp.295-306Wolters Kluwer
摘要:INTRODUCTION:: Anaplastic lymphoma kinase (ALK) rearrangements occur in 1% to 7% of non–small-cell lung cancers (NSCLCs). Crizotinib, an ALK inhibitor, has been demonstrated to provide dramatic clinical benefits in ALK-positive advanced-stage NSCLC. Fluorescent in situ hybri...
作者:Kim Gruber , Heike Horn , Jörg Kalla ...
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2014, Vol.9 (3), pp.307-315Wolters Kluwer
摘要:INTRODUCTION:: The approved dual-color fluorescence in situ hybridization (FISH) test for the detection of anaplastic lymphoma receptor tyrosine kinase (ALK) gene rearrangements in non-small-cell lung cancer (NSCLC) is complex and represents a low-throughput assay difficult to us...
作者:Pasi A. Jänne , Roger B. Cohen , A. Douglas Laird ...
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2014, Vol.9 (3), pp.316-323Wolters Kluwer
摘要:INTRODUCTION:: The primary objectives of this phase I study were to evaluate the safety and maximum tolerated dose (MTD) of SAR245409, a pan-class I phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin inhibitor, combined with erlotinib in patients with advanced sol...
作者:Sebahat Ocak , David B. Friedman , Heidi Chen ...
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2014, Vol.9 (3), pp.324-336Wolters Kluwer
摘要:INTRODUCTION:: Small-cell lung cancer (SCLC) is the most aggressive subtype of lung cancer, with no early detection strategy or targeted therapy currently available. We hypothesized that difference gel electrophoresis (DIGE) may identify membrane-associated proteins (MAPs) s...
作者:Yuki Matsumura , Tomoyuki Hishida , Yoshihisa Shimada ...
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2014, Vol.9 (3), pp.337-344Wolters Kluwer
摘要:INTRODUCTION:: Lymphatic permeation has been reported as a prognostic factor for patients with resected non–small-cell lung cancer (NSCLC). Lymphatic canals are located in both intratumoral and extratumoral areas. Since 2001, we have prospectively evaluated lymphatic permeat...
作者:Robert E. Miller , Jon C. Jones , Mark Tometsko ...
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2014, Vol.9 (3), pp.345-354Wolters Kluwer
摘要:INTRODUCTION:: Bone metastasis is a serious complication in patients with lung cancer, occurring in up to 40% of patients. Tumor cell–mediated osteolysis occurs ultimately through induction of RANK ligand (RANKL) within the bone stroma although this hypothesis has not been t...
作者:Hannah Katcoff , Angela S. Wenzlaff , Ann G. Schwartz
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2014, Vol.9 (3), pp.355-361Wolters Kluwer
摘要:INTRODUCTION:: Although lung cancer is the leading cause of cancer death in women, few studies have investigated the hormonal influence on survival after a lung cancer diagnosis and results have been inconsistent. We evaluated the role of reproductive and hormonal factors in...

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