全部文献期刊会议图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Yoshitomo Hamuro
来源:[J].Journal of The American Society for Mass Spectrometry(IF 3.592), 2017, Vol.28 (5), pp.971-977
摘要:Protein backbone amide hydrogen/deuterium exchange mass spectrometry (HDX-MS) typically utilizes enzymatic digestion after the exchange reaction and before MS analysis to improve data resolution. Gas-phase fragmentation of a peptic fragment prior to MS analysis is a promisin...
作者:Hongyan Ma , Daniel G. Delafield , Zhe Wang ...
来源:[J].Journal of The American Society for Mass Spectrometry(IF 3.592), 2017, Vol.28 (4), pp.655-663
摘要:The microbial secretome, known as a pool of biomass (i.e., plant-based materials) degrading enzymes, can be utilized to discover industrial enzyme candidates for biofuel production. Proteomics approaches have been applied to discover novel enzyme candidates through comparing...
作者:Y. Zhu , H. A. Roy , N. A. Cunningham ...
来源:[J].Journal of The American Society for Mass Spectrometry(IF 3.592), 2017, Vol.28 (11), pp.2423-2437
摘要:Thymidine (dThd) is a fundamental building block of DNA nucleic acids, whereas 5-methyluridine (Thd) is a common modified nucleoside found in tRNA. In order to determine the conformations of the sodium cationized thymine nucleosides [dThd+Na]+ and [Thd+Na]+ ...
作者:Francisca Diana da Silva Araújo , Welington Luiz Araújo , Marcos Nogueira Eberlin
来源:[J].Journal of The American Society for Mass Spectrometry(IF 3.592), 2017, Vol.28 (5), pp.901-907
摘要:Species of genus Burkholderia display different interaction profiles in the environment, causing either several diseases in plants and animals or being beneficial to some plants, promoting their growth, and suppressing phytopathogens. Burkholderia spp. also produce many types of ...
作者:Gaël Picard de Muller , Rima Ait-Belkacem , David Bonnel ...
来源:[J].Journal of The American Society for Mass Spectrometry(IF 3.592), 2017, Vol.28 (12), pp.2635-2645
摘要:Mass spectrometry imaging datasets are mostly analyzed in terms of average intensity in regions of interest. However, biological tissues have different morphologies with several sizes, shapes, and structures. The important biological information, contained in this highly het...
作者:Alice L. Pilo , Feifei Zhao , Scott A. McLuckey
来源:[J].Journal of The American Society for Mass Spectrometry(IF 3.592), 2017, Vol.28 (6), pp.991-1004
摘要:Here, we provide an overview of pathways available upon the gas-phase oxidation of peptides and DNA via ion/ion reactions and explore potential applications of these chemistries. The oxidation of thioethers (i.e., methionine residues and S-alkyl cysteine residues), disulfide...
作者:Richard Y.-C. Huang , Roxana E. Iacob , Stanley R. Krystek ...
来源:[J].Journal of The American Society for Mass Spectrometry(IF 3.592), 2017, Vol.28 (5), pp.795-802
摘要:Aggregation of protein therapeutics has long been a concern across different stages of manufacturing processes in the biopharmaceutical industry. It is often indicative of aberrant protein therapeutic higher-order structure. In this study, the aggregation propensity of a human Fc...
作者:Babak Basiri , Mandi M. Murph , Michael G. Bartlett
来源:[J].Journal of The American Society for Mass Spectrometry(IF 3.592), 2017, Vol.28 (8), pp.1647-1656
摘要:Alkylamines are widely used as ion-pairing agents during LC-MS of oligonucleotides. In addition to a better chromatographic separation, they also assist with the desorption of oligonucleotide ions into the gas phase, cause charge state reduction, and decrease cation adductio...
作者:Lissa C. Anderson , Maria Håkansson , Björn Walse ...
来源:[J].Journal of The American Society for Mass Spectrometry(IF 3.592), 2017, Vol.28 (9), pp.1796-1804
摘要:Structural technologies are an essential component in the design of precision therapeutics. Precision medicine entails the development of therapeutics directed toward a designated target protein, with the goal to deliver the right drug to the right patient at the right time. In t...
作者:Xiaobo Xie , Zhenpeng Wang , Yafeng Li ...
来源:[J].Journal of The American Society for Mass Spectrometry(IF 3.592), 2017, Vol.28 (6), pp.1036-1047
摘要:A liquid sampling-atmospheric pressure afterglow microplasma ionization (LS-APAG) source is presented for the first time, which is embedded with both electrospray ionization (ESI) and atmospheric pressure afterglow microplasma ionization (APAG) techniques. This ion source is...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×