全部文献期刊会议图书|学者科研项目
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作者:Terry L. Ng , Narayana Narasimhan , Neeraj Gupta ...
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2020
摘要:Abstract(#br)Introduction(#br)We evaluated pulmonary adverse events observed within 7 days after drug initiation in phase 1 to phase 3 studies of anaplastic lymphoma kinase (ALK) inhibitor, brigatinib.(#br)Methods(#br)The phase 1/2 study enrolled patients with advanced malig...
作者:Luis Paz-Ares , Tae Min Kim , David Vicente ...
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2020
摘要:Summary(#br)Introduction(#br)The safety and efficacy of bintrafusp alfa, a first-in-class bifunctional fusion protein composed of the extracellular domain of the TGF-βRII receptor (a TGF-β “trap”) fused to a human IgG1 antibody blocking PD-L1, was evaluated in patients ...
作者:Laura Mezquita , Maria Jove , Ernest Nadal ...
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2020
摘要:Abstract(#br)Background(#br)Actionable somatic molecular alterations are found in 15 to 20% of non-small cell lung cancer (NSCLC) in the Caucasians. NSCLC is a tumor observed in patients with germline- TP53 variants causing Li-Fraumeni syndrome (LFS), but its somatic molecular pr...
作者:William D. Travis , Sanja Dacic , Ignacio Wistuba ...
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2020
摘要:Abstract(#br)Currently, there is no established guidance on how to process and evaluate resected lung cancer specimens after neoadjuvant therapy in the setting of clinical trials and clinical practice. There is also a lack of precise definitions on the degree of pathologic respon...
作者:Lise Lurienne , Julie Cervesi , Lola Duhalde ...
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2020
摘要:Abstract(#br)Introduction(#br)Immune checkpoint inhibitors (ICI) have dramatically improved patient outcomes in a variety of tumor types, but with variable efficacy. Recent research has suggested that antibiotic- induced disruption of the microbiota may impact ICI efficacy.(...
作者:Sufang Tian , Weidong Hu , Li Niu ...
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2020
摘要:Abstract(#br)There is currently a lack of pathologic data on the novel coronavirus (severe acute respiratory syndrome coronavirus 2) pneumonia, or coronavirus disease 2019 (COVID-19), from autopsy or biopsy. Two patients who recently underwent lung lobectomies for adenocarcinoma ...
作者:Cristina M. DeCesaris , Rachel McCarroll , Mark V. Mishra ...
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2020
摘要:Abstract(#br)Introduction(#br)Re-irradiation (re-RT) for locoregionally recurrent esophageal and gastroesophageal junction (GEJ) cancer and de novo esophageal/GEJ cancer arising in-field after a course of prior radiation poses significant treatment challenges given the sensitivit...

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