全部文献期刊会议图书|学者科研项目
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作者:Kai Zhang , Jing Lu , Lei Yao
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2020, Vol.142 (1), pp.26-33
摘要:Abstract(#br)Cedrol, mainly derived from Juniperus virginiana L. essential oil, has been demonstrated the anxiolytic effect, although its mechanism of action is still not fully established. In the present study, male ICR mice were submitted to the elevated plus maze (EPM) an...
作者:Takafumi Horishita , Yuichi Ogata , Reiko Horishita ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2020, Vol.142 (4), pp.140-147
摘要:Abstract(#br)Carvacrol is the predominant monoterpene in essential oils from many aromatic plants. Several animal studies showing analgesic effects of carvacrol indicate potential of carvacrol as a new medication for patients with refractory pain. Voltage-gated sodium channe...
作者:Noha F. Abdelkader , Mohammed Elyamany , Amany M. Gad ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2020
摘要:Abstract(#br)Valproic acid is a commonly used drug for many psychiatric disorders, particularly for epilepsy. However, it has been reported that its use is associated with possible side effects including hepatotoxicity.(#br)The present study investigated the hepatoprotective...
作者:Ana Letícia Júlio de Souza , Aline Beatriz Mahler Pereira , Jhony Robison de Oliveira ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2020, Vol.142 (4), pp.157-164
摘要:Abstract(#br)The house dust mite allergen Dermatophagoides pteronyssinus (Der p) is a major driver of allergic asthma. Studies from our group demonstrated anti-eosinophilic effects of ethanolic extract of Lafoensia pacari stem bark (and ellagic acid, isolated from L. pacari ...
作者:Shizuo Yamada , Shiori Kuraoka , Yoshihiko Ito ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2020, Vol.142 (3), pp.127-130
摘要:Abstract(#br)In vitro and in vivo binding sites of [ 3 H]-labeled 5-hydroxymethyltolterodine (5-HMT), a new radioligand for labeling muscarinic receptors in rat tissues were characterized. Specific [ 3 H]5-HMT binding in rat tissues was saturable and of high affinity in each tiss...
作者:Song Zuo , Linling Li , Le Jiang ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2020
摘要:Abstract(#br)Acute inflammation often contributes to the increased arrhythmogenesis in the cardiomyocytes. We investigated the protective effects of pravastatin on calcium disorders induced by acute administration of pro-inflammatory cytokines in isolated ventricular myocytes and...
作者:Tatsuya Tsuda , Masaki Imanishi , Mizuho Oogoshi ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2020, Vol.142 (3), pp.109-115
摘要:Abstract(#br)Arterial calcification, a risk factor of cardiovascular events, develops with differentiation of vascular smooth muscle cells (VSMCs) into osteoblast-like cells. Cyclophilin A (CypA) is a peptidyl-prolyl isomerase involved in cardiovascular diseases such as atheroscl...
作者:Shinichi Harada , Wakako Fujita-Hamabe , Shogo Tokuyama
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2020, Vol.142 (4), pp.176-176
摘要:This article has been retracted: please see Elsevier Policy on Article Withdrawal ( https://www.elsevier.com/about/our-business/policies/article-withdrawal ).(#br)This article has been retracted at the request of the Authors. In Figure 1C some of the numbers of the original raw d...
作者:Ai Goto , Kengo Sakamoto , Mihoko Hagiwara-Nagasawa ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2020, Vol.142 (4), pp.172-175
摘要:Abstract(#br)It has been difficult to experimentally reproduce synergistic effects of ketoconazole on terfenadine-induced torsade de pointes. We assessed proarrhythmic effects of terfenadine (30 mg/kg, p.o.) with/without ketoconazole (100 mg/kg, p.o.) pretreatment using the chron...
作者:Huiyuan Hu , Shi Zhou , Xiaodong Sun ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2020, Vol.142 (4), pp.131-139
摘要:Abstract(#br)N -methyl berbamine ( N -MB) is a berberine derivative. Its analogue berbamine has been reported to have remarkable antiarrhythmic and ischemic protective effects. However, the pharmacological effects of N -MB are ill-defined. In this study, molecular docking was use...

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