全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Qiaohua Peng , Jiale Qin , Yanan Zhang ...
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)Springer
摘要:Cancer stem cells (CSCs) are regarded as the main cell type responsible for the initiation, metastasis, drug resistance, and recurrence of cancer. But the mechanism by which cancer stem cells maintain their stemness remains unclear.
作者:Chao Zhang , Xin Zhang , Ran Xu ...
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)Springer
摘要:Glioblastoma multiforme (GBM) is characterized by lethal aggressiveness and patients with GBM are in urgent need for new therapeutic avenues to improve quality of life. Current studies on tumor invasion focused on roles of cytokines in tumor microenvironment and numerous evi...
作者:Qifeng Wang , Hualei Gan , Chengshu Chen ...
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)Springer
摘要:Renal cancers account for more than 3% of all adult malignancies and cause more than 23,400 deaths per year in China alone. The four most common types of kidney tumours include clear cell, papillary, chromophobe and benign oncocytoma. These histological subtypes vary in their cli...
作者:Xian Qin , Changsheng Li , Tao Guo ...
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)Springer
摘要:Infection with the hepatitis B virus (HBV) is closely associated with the development of hepatocellular carcinoma (HCC). The osmoregulatory transcription factor nuclear factor of activated T-cells 5 (NFAT5) has been shown to play an important role in the development of many types...
作者:Enrica Flori , Eleonora Rosati , Giorgia Cardinali ...
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)Springer
摘要:The α-Melanocyte Stimulating Hormone (αMSH)/Melanocortin-1 receptor (MC1R) interaction promotes melanogenesis through the cAMP/PKA pathway. The direct induction of this pathway by Forskolin (FSK) is also known to enhance melanocyte proliferation. αMSH acts as a mitogenic age...
作者:Liwei Lang , Chloe Shay , Xiangdong Zhao ...
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)Springer
摘要:Although major improvements have been made in surgical management, chemotherapeutic, and radiotherapeutic of prostate cancer, many prostate cancers remain refractory to treatment with standard agents. Therefore, the identification of new molecular targets in cancer progression an...
作者:Monika Jaruskova , Nikola Curik , Rajna Hercog ...
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)Springer
摘要:Through high-throughput next-generation sequencing of promoters of solute carrier and ATP-binding cassette genes, which encode drug transporters, we aimed to identify SNPs associated with the response to imatinib administered for first-line treatment of patients with chronic myel...
作者:Anna Shvartsur , Kevin B. Givechian , Hermes Garban ...
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)Springer
摘要:Multiple myeloma (MM) is a clonal plasma-cell neoplastic disorder arising from an indolent premalignant disease known as monoclonal gammopathy of undetermined significance (MGUS). MM is a biologically complex heterogeneous disease reflected by its variable clinical responses...
作者:Shanyang He , Gang Niu , Jianhong Shang ...
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)Springer
摘要:Chemo-resistance is a leading cause of tumor relapse and treatment failure in patients with ovarian cancer. The identification of effective strategies to overcome drug resistance will have a significant clinical impact on the disease.

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