全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Junya Ono , Hiroaki Shime , Hiromi Takaki ...
来源:[J].Journal of Biomedical Science, 2017, Vol.24 (1)Springer
摘要:Intestinal tumorigenesis is promoted by myeloid differentiation primary response gene 88 (MyD88) activation in response to the components of microbiota in Apc Min/+ mice. Microbiota also contains double-stranded RNA (dsRNA), a ligand for TLR3, which activates the tol...
作者:Anja Schwarz , Gabriel A. Bonaterra , Hans Schwarzbach ...
来源:[J].Journal of Biomedical Science, 2017, Vol.24 (1)Springer
摘要:Oxidized low-density lipoprotein (oxLDL) mediates the transformation of macrophages (MΦ) to cholesterol-rich foam cells and the release of pro-inflammatory cytokines during atherogenesis. JAB1 (Jun activation domain binding protein-1) is present in all stages of human plaque...
作者:Chih-Hao Wang , Yau-Huei Wei
来源:[J].Journal of Biomedical Science, 2017, Vol.24 (1)Springer
摘要:Metabolic diseases such as obesity, type 2 diabetes (T2D) and insulin resistance have attracted great attention from biomedical researchers and clinicians because of the astonishing increase in its prevalence. Decrease in the capacity of oxidative metabolism and mitochondrial dys...
作者:Guan-Ling Lu , Hau-Jie Yau , Lih-Chu Chiou
来源:[J].Journal of Biomedical Science, 2017, Vol.24 (1)Springer
摘要:Long-term potentiation (LTP) is well recognized as a cellular-correlated synaptic plasticity of learning and memory. However, its reversal forms of synaptic plasticity, depotentiation, is less studied and its association with behaviors is also far from clear. Previously, we have ...
作者:Xing Shen , Bo Pan , Huiming Zhou ...
来源:[J].Journal of Biomedical Science, 2017, Vol.24 (1)Springer
摘要:Bone marrow derived stem cells (BMSCs) have the potential to differentiate into cardiomyocytes, but the rate of differentiation is low and the mechanism of differentiation is unclear completely. Here, we aimed to investigate the role of miR1-2 in differentiation of mouse BMSCs in...
作者:Shih-Ya Hung , Wen-Mei Fu
来源:[J].Journal of Biomedical Science, 2017, Vol.24 (1)Springer
摘要:Alzheimer’s disease (AD) is a major form of senile dementia, characterized by progressive memory and neuronal loss combined with cognitive impairment. AD is the most common neurodegenerative disease worldwide, affecting one-fifth of those aged over 85 years. Recent therapeut...
作者:Omar A.H. Ahmed-Farid , Maha Nasr , Rania F. Ahmed ...
来源:[J].Journal of Biomedical Science, 2017, Vol.24 (1)Springer
摘要:Malnutrition resulting from protein and calorie deficiency continues to be a major concern worldwide especially in developing countries. Specific deficiencies in the protein intake can adversely influence reproductive performance. The present study aimed to evaluate the effects o...
作者:Jie Li , Yingjie Li , Bin Wang ...
来源:[J].Journal of Biomedical Science, 2017, Vol.24 (1)Springer
摘要:Numerous studies have shown that Id-1 (Inhibitor of differentiation 1) is upregulated in several cancers and associated with tumor malignant characters. However, the clinical significance and biological role of Id-1 in non-small cell lung cancer (NSCLC) remains unclear.
作者:Yan-li Guo , Bao-En Shan , Wei Guo ...
来源:[J].Journal of Biomedical Science, 2017, Vol.24 (1)Springer
摘要:The DACT (Dishevelled-associated antagonist of β-catenin) family of scaffold proteins may play important roles in tumorigenesis. However, the epigenetic changes of DACT1, 2, 3 and their effect on esophageal squamous cell carcinoma (ESCC) have not been investigated so far. Th...
作者:Jing-Wen Shih , Hsing-Jien Kung
来源:[J].Journal of Biomedical Science, 2017, Vol.24 (1)Springer
摘要:Hypoxia is a classic feature of the tumor microenvironment with a profound impact on cancer progression and therapeutic response. Activation of complex hypoxia pathways orchestrated by the transcription factor HIF (hypoxia-inducible factor) contributes to aggressive phenotypes an...

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