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作者:Yujia Huang , Michelle Cua , Joshua Brake ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2020, Vol.25 (2), pp.025002-025002
摘要:Significance: Ultrasound-assisted optical imaging techniques, such as ultrasound-modulated optical tomography, allow for imaging deep inside scattering media. In these modalities, a fraction of the photons passing through the ultrasound beam is modulated. The efficiency by w...
作者:LeMoyne Habimana-Griffin , Dezhuang Ye , Julia Carpenter ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2020, Vol.25 (2), pp.026004-026004
摘要:Significance: The blood–brain barrier (BBB) is a major obstacle to detecting and treating brain tumors. Overcoming this challenge will facilitate the early and accurate detection of brain lesions and guide surgical resection of tumors.;; Aim: We generated an orthotopic brain...
作者:Van K. Lam , Thanh Nguyen , Vy Bui ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2020, Vol.25 (2), pp.026002-026002
摘要:Significance : We introduce an application of machine learning trained on optical phase features of epithelial and mesenchymal cells to grade cancer cells’ morphologies, relevant to evaluation of cancer phenotype in screening assays and clinical biopsies.;; Aim : Our objecti...
作者:Anh Phong Tran , Steven L. Jacques
来源:[J].Journal of Biomedical Optics(IF 2.881), 2020, Vol.25 (2), pp.025001-025001
摘要:Significance: Monte Carlo (MC) light transport simulations are most often performed in regularly spaced three-dimensional voxels, a type of data representation that naturally struggles to represent boundary surfaces with curvature and oblique angles. Not accounting properly for s...
作者:Soohyun Lee , Shuwen Wei , Shoujing Guo ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2020, Vol.25 (2), pp.026001-026001
摘要:Significance: Selective retina therapy (SRT) selectively targets the retinal pigment epithelium (RPE) and reduces negative side effects by avoiding thermal damages of the adjacent photoreceptors, the neural retina, and the choroid. However, the selection of proper laser ener...
作者:Subhasri Chatterjee , Zaibaa Patel , Mohamed A. Thaha ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2020, Vol.25 (2), pp.027001-027001
摘要:Significance: Colorectal cancer is one of the major causes of cancer-related deaths worldwide. Surgical removal of the cancerous growth is the primary treatment for this disease. A colorectal cancer surgery, however, is often unsuccessful due to the anastomotic failure that ...
作者:Shona Stewart , Marlena Darr , Heather Gomer ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2020, Vol.25 (2), pp.026003-026003
摘要:Significance : A key risk faced by oncological surgeons continues to be complete removal of tumor. Currently, there is no intraoperative imaging device to detect kidney tumors during excision.;; Aim : We are evaluating molecular chemical imaging (MCI) as a technology for real-tim...
作者:Andrew D. Thrapp , Michael R. Hughes
来源:[J].Journal of Biomedical Optics(IF 2.881), 2020, Vol.25 (2), pp.026501-026501
摘要:Significance : Confocal laser scanning enables optical sectioning in clinical fiber bundle endomicroscopes, but lower-cost, simplified endomicroscopes use widefield incoherent illumination instead. Optical sectioning can be introduced in these simple systems using structured illu...
作者:Mikael T. Erkkilä , David Reichert , Nancy Hecker-Denschlag ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2020, Vol.25 (07), pp.071202
摘要:Significance: 5-Aminolevulinic acid (5-ALA-based fluorescence guidance in conventional neurosurgical microscopes is limited to strongly fluorescent tumor tissue. Therefore, more sensitive, intrasurgical 5-ALA fluorescence visualization is needed.Aim: Macroscopic fluorescence...
作者:Eric Seifert , Jan Tode , Amelie Pielen ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2018, Vol.23 (11), pp.115002-115002
摘要:Selective retina therapy (SRT) targets the retinal pigment epithelium (RPE) with pulsed laser irradiation by inducing microbubble formation (MBF) at the intracellular melanin granula, which leads to selective cell disruption. The following wound healing process rejuvenates t...

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