全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Shui-Long Guo, Zheng Peng, Xue Yang, Kai-Ji Fan, Hui Ye, Zhen-Hua Li, Yan Wang, Xiao-Li Xu, Jun Li, You-Liang Wang, Yan Teng, Xiao Yang
来源:[J].International Journal of Biological Sciences(IF 3.168), 2011, Vol.7 (5), pp.567DOAJ
摘要:Accumulating evidence has shown that miRNAs are aberrantly expressed in human gastric cancer and crucial to tumorigenesis. Herein, we identified the role of miR-148a in gastric cell proliferation. miR-148a knockdown inhibited cell proliferation in gastric cancer cell lines. Conve...
作者:Chengwen Chen, Xuping Fu, Deqiang Zhang, Yuan Li, Yi Xie, Yao Li, Yan Huang
来源:[J].International Journal of Biological Sciences(IF 3.168), 2011, Vol.7 (5), pp.551DOAJ
摘要:Background : Discovery of the progression-associated genes and pathways in lung adenocarcinoma (LAD) has important implications in understanding the molecular mechanism of tumor development. However, few studies had been performed to focus on the changes of pathways in lung adeno...
作者:Hua Wang, Fouad Lafdil, Xiaoni Kong, Bin Gao
来源:[J].International Journal of Biological Sciences(IF 3.168), 2011, Vol.7 (5), pp.536DOAJ
摘要:Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that is activated by many cytokines and growth factors and plays a key role in cell survival, proliferation, and differentiation. STAT3 activation is detected virtually in all rodent models of li...
作者:Naoki Oishi, Xin Wei Wang
来源:[J].International Journal of Biological Sciences(IF 3.168), 2011, Vol.7 (5), pp.517DOAJ
摘要:The cancer stem cell (CSC) hypothesis was first proposed over 40 years ago. Advances in CSC isolation were first achieved in hematological malignancies, with the first CSC demonstrated in acute myeloid leukemia. However, using similar strategies and technologies, and taking ...
作者:Qingtian Li, Jianming Xu
来源:[J].International Journal of Biological Sciences(IF 3.168), 2011, Vol.7 (5), pp.505DOAJ
摘要:The nuclear receptor coactivator-6 (NCOA6, AIB3, PRIP, ASC-2, TRBP, RAP250 or NRC) is a co-activator for nuclear hormone receptors and certain other transcription factors. NCOA6 plays an important role in embryonic development, adipocyte differentiation, metabolism and breas...
作者:Xiu-Li Xu, Xia Wang, Zhao-Li Chen, Min Jin, Wu Yang, Guo-Fan Zhao, Jun-Wen Li
来源:[J].International Journal of Biological Sciences(IF 3.168), 2011, Vol.7 (5), pp.496DOAJ
摘要:Objective : Grb2-associated binder 2 (Gab2), a member of the family of Gab scaffolding adaptors, transmits and amplifies the signals from receptor tyrosine kinases. A recent study demonstrated that Gab2 was over-expressed in breast cancers and metastatic melanomas, and Gab2 was a...
作者:KaiKun Luo, Jun Xiao, ShaoJun Liu, Jing Wang, WeiGuo He, Jie Hu, QinBo Qin, Chun Zhang, Min Tao, Yun Liu
来源:[J].International Journal of Biological Sciences(IF 3.168), 2011, Vol.7 (4), pp.487DOAJ
摘要:In many species of aquaculture importance, all-female and sterile populations possess superior productivity due to faster growth and a relatively homogenous size of individuals. However, the production of all-female and sterile fish in a large scale for aquaculture is a chal...
作者:Da-Ji Luo, Wei Hu, Shang-Ping Chen, Zuo-Yan Zhu
来源:[J].International Journal of Biological Sciences(IF 3.168), 2011, Vol.7 (4), pp.476DOAJ
摘要:Somatic cell nuclear transfer (SCNT) has been performed extensively in fish since the 1960s with a generally low efficiency of approximately 1%. Little is known about somatic nuclear reprogramming in fish. Here, we utilized the zebrafish as a model to study reprogramming eve...
作者:Tongming Liu, Ling Liu, Qiwei Wei, Yunhan Hong
来源:[J].International Journal of Biological Sciences(IF 3.168), 2011, Vol.7 (4), pp.469DOAJ
摘要:Sperm nuclear transfer or intracytoplasmic sperm injection (ICSI) is a powerful assisted reproductive technology (ART) for treating human male infertility. Controversial reports of increased birth defects have raised concerns about the ART's safety. The cause for birth defects, h...
作者:Manabu Hattori, Hisashi Hashimoto, Ekaterina Bubenshchikova, Yuko Wakamatsu
来源:[J].International Journal of Biological Sciences(IF 3.168), 2011, Vol.7 (4), pp.460DOAJ
摘要:We previously established a novel method for nuclear transfer in medaka ( Oryzias latipes ) using non-enucleated, diploidized eggs as recipients for adult somatic cell nuclei. Here we report the first attempt to apply this method to another fish species. To examine suitability of...

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