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作者:Lei-Lei Liu , Nathan J. Spix , Dao-Qi Zhang
来源:[J].Frontiers in Cellular Neuroscience(IF 4.469), 2017, Vol.11
摘要:Recently, a line of evidence has demonstrated that the vertebrate retina possesses a novel retrograde signaling pathway. In this pathway, phototransduction is initiated by the photopigment melanopsin, which is expressed in a small population of retinal ganglion cells. These ...
作者:Jun Yang , Yujie Xiao , Liang Li ...
来源:[J].Frontiers in Cellular Neuroscience(IF 4.469), 2019, Vol.13
摘要:Spiking activities of midbrain dopaminergic neurons are critical for key brain functions including motor control and affective behaviors. Voltage-gated Na+ channels determine neuronal excitability and action potential (AP) generation. Previous studies on dopaminergic neuron ...
作者:Gaia Gestri , Naiara Bazin-Lopez , Clarissa Scholes ...
来源:[J].Frontiers in Cellular Neuroscience(IF 4.469), 2018, Vol.12
摘要:Coloboma is a defect in the morphogenesis of the eye that is a consequence of failure of choroid fissure fusion. It is among the most common congenital defects in humans and can significantly impact vision. However, very little is known about the cellular mechanisms that regulate...
作者:Shujuan Meng , Shujuan Meng , Shujuan Meng ...
来源:[J].Frontiers in Cellular Neuroscience(IF 4.469), 2019, Vol.13
摘要:Canonical epigenetic modifications, including DNA methylation, histone modification and chromatin remodeling, play a role in numerous life processes, particularly neurodevelopment. Epigenetics explains the development of cells in an organism with the same DNA sequence into d...
作者:Ana Rita Costa , Ana Rita Costa , Ana Rita Costa ...
来源:[J].Frontiers in Cellular Neuroscience(IF 4.469), 2019, Vol.13
摘要:Opioids play a major role at descending pain modulation but the effects of neuropathic pain on the brain opioidergic system remain understudied. Since descending facilitation is enhanced during neuropathic pain, we studied the opioidergic modulation of the dorsal reticular n...
作者:Romain Helleringer , Oana Chever , Hervé Daniel ...
来源:[J].Frontiers in Cellular Neuroscience(IF 4.469), 2017, Vol.11
摘要:During brain ischemia, intense energy deficiency induces a complex succession of events including pump failure, acidosis and exacerbated glutamate release. In the cerebellum, glutamate is the principal mediator of Purkinje neuron anoxic depolarization during episodes of oxygen an...
作者:Bernd Kuhn , Christopher J. Roome
来源:[J].Frontiers in Cellular Neuroscience(IF 4.469), 2019, Vol.13
摘要:ANNINE-6 and ANNINE-6plus are voltage-sensitive dyes that when combined with two-photon microscopy are ideal for recording of neuronal voltages in vivo, in both bulk loaded tissue and the dendrites of single neurons. Here, we describe in detail but for a broad audience the voltag...
作者:Werner Kilb , Atsuo Fukuda
来源:[J].Frontiers in Cellular Neuroscience(IF 4.469), 2017, Vol.11
摘要:A variety of experimental studies demonstrated that neurotransmitters are an important factor for the development of the central nervous system, affecting neurodevelopmental events like neurogenesis, neuronal migration, programmed cell death, and differentiation. While the role o...
作者:Xiangyi Wen , Xiangyi Wen , Grant W. Saltzgaber ...
来源:[J].Frontiers in Cellular Neuroscience(IF 4.469), 2017, Vol.11
摘要:Accompanying sustained release in darkness, rod and cone photoreceptors exhibit rapid endocytosis of synaptic vesicles. Membrane capacitance measurements indicated that rapid endocytosis retrieves at least 70% of the exocytotic membrane increase. One mechanism for rapid endo...
作者:Lara Bieler , Lara Bieler , Michael Vogl ...
来源:[J].Frontiers in Cellular Neuroscience(IF 4.469), 2019, Vol.13
摘要:Restoration of neuronal connectivity after lesion of the central nervous system, such as spinal cord injury, is one of the biggest challenges in modern medicine. In particular, the accumulation of axon growth inhibitory factors at the site of injury constitutes a major obsta...

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