全部文献期刊会议图书|学者科研项目
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作者:Qiong Xu , Jianxiong Chen , Man Peng ...
来源:[J].Experimental Cell Research(IF 3.557), 2020
摘要:Abstract(#br)Current studies have shown that POTE ankyrin domain family members have high expressions as tumor antigens in malignant tumors, such as prostate cancer, ovarian cancer, breast cancer and the like. POTEE is a member of the POTE anchor protein family E. However, its ro...
作者:Xuguang Li , Guang Chu , Feng Zhu ...
来源:[J].Experimental Cell Research(IF 3.557), 2020, Vol.386 (1)
摘要:Abstract(#br)Background(#br)Emerging evidence demonstrates that epoxyeicosatrienoic acids (EETs) as important active eicosanoids that regulate cardiovascular homeostasis, but the mechanisms underlying its favorable anti-hypertrophic benefits in overpressure model remain obsc...
作者:Atsuki En , Yuki Takauji , Dai Ayusawa ...
来源:[J].Experimental Cell Research(IF 3.557), 2020
摘要:Abstract(#br)Cellular senescence is a phenomenon of irreversible growth arrest of mammalian somatic cells. Senescent cells increase the production of secretory proteins such as inflammatory cytokines, a phenomenon termed senescence-associated secretory phenotype (SASP). SASP is k...
作者:Marlies Peeters , Gerben Menschaert
来源:[J].Experimental Cell Research(IF 3.557), 2020
摘要:Abstract(#br)Growing evidence illustrates the shortcomings on the current understanding of the full complexity of the proteome. Previously overlooked small open reading frames (sORFs) and their encoded microproteins have filled important gaps, exerting their function as biologica...
作者:Peihang Jing , Shengli Zhou , Pengpeng Xu ...
来源:[J].Experimental Cell Research(IF 3.557), 2020, Vol.386 (2)
摘要:Abstract(#br)Hypopharyngeal squamous cell carcinoma (HSCC) is a relatively rare malignancy and has the worst prognosis among head and neck cancer. Metastasis is the major cause of poor prognosis in HSCC patients. In this study, we found that 3-phosphoinositide-dependent protein k...
作者:Jing Li , Jiaqi He , Xiang Zhang ...
来源:[J].Experimental Cell Research(IF 3.557), 2020, Vol.388 (1)
摘要:Abstract(#br)Age-related macular degeneration is a progressive ocular disease that is the leading cause of vision loss among elderly. AMD usually is divided into two types: wet and dry AMD, which is linked with inflammation. Choroidal Neovascularization (CNV) formation or we...
作者:Dai Yuedi , Liu Houbao , Lu Pinxiang ...
来源:[J].Experimental Cell Research(IF 3.557), 2020, Vol.388 (1)
摘要:Abstract(#br)Pancreatic cancer is one of the most common malignancies in the world. Senescence is frequently observed in the progression of pancreatic cancer. In a previous study, we showed that KLF2 inhibited the growth and migration of pancreatic cancer. However, the mechanisms...
作者:Shotaro Yamano , Makoto Kimura , Yu Chen ...
来源:[J].Experimental Cell Research(IF 3.557), 2020, Vol.386 (1)
摘要:Abstract(#br)IER5 gene encodes an activator of HSF1 and is a p53 target gene. The IER5 protein forms a ternary complex with HSF1 and PP2A, and promotes PP2A-dependent dephosphorylation of HSF1 at a number of serine and threonine residues. This hypo-phosphorylated form of HSF...
作者:Jia-Hua Zhang , Jia-Hui Deng , Xia-Li Yao ...
来源:[J].Experimental Cell Research(IF 3.557), 2020, Vol.386 (1)
摘要:Abstract(#br)The immune system is felt to play an essential role in pulmonary fibrosis (PF). CD4 + CD25 + regulatory T cells (Tregs) are crucial in maintaining immune tolerance and immune homeostasis, but their role in the pathogenesis of PF is controversial and still unclea...

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