全部文献期刊会议图书|学者科研项目
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作者:Sajjad Molavipordanjani , Shabanali Khodashenas , Seyed Mohammad Abedi ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2020
摘要:Abstract(#br)Exosomes represent unique features including nontoxicity, non-immunogenicity, biodegradability, and targeting ability that make them suitable candidates for clinical applications. Therefore, in this study, a radiolabel HER2 targeted exosomes ( 99m Tc-exosomes) was pr...
作者:Faheem Hyder Pottoo , Nahida Tabassum , Md. Noushad Javed ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2020, Vol.146
摘要:Abstract(#br)The evidence to guide clinicians regarding rationale polytherapy with current antiepileptic drugs (AEDs) is lacking, and current practice recommendations are largely empirical. The excessive drug loading with combinatorial therapies of existing AEDs are associated wi...
作者:Diego Lucero-Borja , Xavier Subirats , Rafael Barbas ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2020
摘要:Abstract(#br)The solubility of three drugs (glimepiride, pioglitazone, sibutramine) with different acid/base properties and expected supersaturation behavior was examined in detail using the shake-flask (SF) and potentiometric (CheqSol) methods. Both uncharged (free) species...
作者:Wesam G. Ammari , Ghaleb A. Oriquat , Mark Sanders
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2020, Vol.147
摘要:Abstract(#br)Background(#br)Coordination between actuation of a pressurized metered dose inhaler (pMDI) and inhalation is a critical manoeuvre that many patients fail to perform correctly. pMDIs connected to spacers do not require hand-lung coordination. This study evaluated...
作者:Dana E. Moseson , Andrew S. Parker , Stephen P. Beaudoin ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2020, Vol.146
摘要:Abstract(#br)The solubility advantage of amorphous solid dispersions (ASDs) is contingent upon supersaturation being generated and maintained. If crystals are present within an ASD, these crystals directly result in lost solubility advantage, and may also seed crystal growth...
作者:Mayre Aparecida Borges da Costa , Amanda Lemette T. Brandão , Jorge G.F. Santos ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2020, Vol.146
摘要:Abstract(#br)The evaluation of faults in a multipurpose pharmaceutical pilot plant used for production of polymer particles was performed, integrating traditional Fault Tree Analyses (FTA) and Monte Carlo procedures and employing tools of the quality risk management methodol...
作者:Saba Ismail , Sajjad Ahmad , Syed Sikander Azam
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2020, Vol.146
摘要:Abstract(#br)Healthcare associated infections (HAIs) are major cause of elevated mortality, morbidity, and high healthcare costs. Development of a vaccine targeting these pathogens could benefit in reducing HAIs count and excessive use of antibiotics. This work aimed to design a ...
作者:Xiling Jiang , Xi Chen , Pharavee Jaiprasart ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2020, Vol.146
摘要:Abstract(#br)T cell-redirecting bispecific antibodies (bsAbs) are highly potent tumor-killing molecules. Following bsAb mediated engagement with target cells, T cells get activated and kill target cells while inducing cytokine release, which at higher levels may lead to life...
作者:Sanja Asikainen , Jukka Seppälä
来源:[J].European Journal of Pharmaceutics and Biopharmaceutics(IF 3.826), 2020, Vol.150, pp.33-42
摘要:Abstract(#br)Photo-crosslinkable polymers have a great potential for the delivery of sensitive drugs. They allow preparation of drug releasing devices by photo-crosslinking, thus avoiding high processing temperatures. In this study, the hydrolysis behavior and drug release of thr...

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