全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Kierkus Jaroslaw , Furmaga-Jablonska Wanda , Sullivan Janice E ...
来源:[J].Digestive Diseases and Sciences, 2010, Vol.56 (2), pp.425-34PubMed
摘要:Limited data on proton pump inhibitors in infants led regulatory agencies to request sponsors to conduct pediatric studies.;;To determine the pharmacodynamic response to pantoprazole in infants with GERD to aid the dose selection for an efficacy study.;;In two open-label stu...
作者:Meek Patrick D , Evang Samuel D , Tadrous Mina ...
来源:[J].Digestive Diseases and Sciences, 2010, Vol.56 (1), pp.7-18PubMed
摘要:Anticholinergic drugs are commonly prescribed for symptomatic treatment of overactive bladder (OAB). While recent meta-analyses have characterized the prevalence of dry mouth among patients utilizing OAB medications, prevalence of constipation has not been systematically rev...
作者:Thakkar Kalpesh , Dorsey Faith , Gilger Mark A
来源:[J].Digestive Diseases and Sciences, 2010, Vol.56 (2), pp.488-93PubMed
摘要:Endoscopy is performed frequently in children with chronic abdominal pain (CAP), but its impact on clinical management is unclear.;;We aimed to examine the frequency of changes in immediate medical management resulting from endoscopy with biopsy evaluating CAP in children.;;We co...
作者:Redlak Maria J , Miller Thomas A
来源:[J].Digestive Diseases and Sciences, 2010, Vol.56 (2), pp.323-9PubMed
摘要:The heat shock protein 90 (HSP90) plays a crucial role in the stability of several proteins that are essential for cell survival and for malignant transformation. The binding of HSP90 with pro-survival kinase Akt prevents proteosomal degradation of Akt and contributes to the...
作者:Greenstein Robert J , Su Liya , Brown Sheldon T
来源:[J].Digestive Diseases and Sciences, 2010, Vol.56 (2), pp.368-75PubMed
摘要:Without known mechanisms of action, Crohn's disease is exacerbated, and ulcerative colitis is improved, by the use of tobacco. Mycobacterium avium subspecies paratuberculosis (MAP) may be zoonotic. We hypothesized that tobacco components might alter the growth kinetics of MA...
作者:Ali Massud , Ward Greg , Staley Doug ...
来源:[J].Digestive Diseases and Sciences, 2010, Vol.56 (2), pp.586-90PubMed
摘要:Pancreatobiliary disease is increased in elderly patients. Because of significant comorbidities, these patients may be at greater risk of developing complications related to endoscopic retrograde cholangiopantreatography (ERCP).;;The purpose of this study was to compare the indic...
作者:Cheong Jae Youn , Um Soon Ho , Seo Yeon Seok ...
来源:[J].Digestive Diseases and Sciences, 2010, Vol.56 (2), pp.555-63PubMed
摘要:The majority of non-invasive markers of liver fibrosis have been developed in patients with chronic hepatitis C. We aimed to develop a formula for predicting significant fibrosis in patients with chronic viral hepatitis and to compare the usefulness of published models deriv...
作者:Despott E J , Gabe S , Tripoli E ...
来源:[J].Digestive Diseases and Sciences, 2010, Vol.56 (2), pp.494-8PubMed
摘要:Although direct percutaneous endoscopic jejunal feeding tube placement is an increasingly accepted method of providing small-bowel access for long-term enteral nutrition, it is reliant on push enteroscopy and remains a technically challenging procedure with significant failure ra...
作者:Chiurillo Miguel Angel , Moran Yeinmy H , Cañas Miryan ...
来源:[J].Digestive Diseases and Sciences, 2010, Vol.56 (2), pp.449-56PubMed
摘要:The cag pathogenicity island (cag-PAI) is one of the major virulence factors of Helicobacter pylori, showing considerable geographic variation.;;We investigated the prevalence of cagA, cagE, and cagT genes of cag-PAI and their association with proinflammatory IL-1B-511/-31/+3954 ...
作者:Ghevariya Vishal , Anand Sury
来源:[J].Digestive Diseases and Sciences, 2010, Vol.56 (2), pp.279-84PubMed
摘要:The gastrointestinal (GI) tract handles a complex task of nutrient absorption and excretion of excess fluid, electrolytes, and toxic substances. GI epithelium is under constant proliferation and renewal. Differentiation of colonocytes occurs as they migrate from the basal layer t...

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