全部文献期刊会议图书|学者科研项目
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作者:Gongming Gao , Haibo Li , Yongjing Huang ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2018, Vol.50 (4), pp.1510-1521DOAJ
摘要:Background/Aims: Periodic mechanical stress has been shown to promote extracellular matrix (ECM) synthesis and cell migration of nucleus pulposus (NP) cells, however, the mechanisms need to be fully elucidated. The present study aimed to investigate the signal transduction pathwa...
作者:Ilona Zareba , Arkadiusz Surazynski , Marcin Chrusciel ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2017, Vol.43 (2), pp.670-684DOAJ
摘要:Background/Aims: The effect of impaired intracellular proline availability for proline dehydrogenase/proline oxidase (PRODH/POX)-dependent apoptosis was studied. Methods: We generated a constitutively knocked-down PRODH/POX MCF-7 breast cancer cell line (MCF-7shPRODH/POX) as a mo...
作者:Dong Wang , Zhi-Ming Wang , Sai Zhang ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2018, Vol.50 (6), pp.2017-2028DOAJ
摘要:Background/Aims: Canopy homolog 2 (CNPY2) is a signature gene highly associated with tumor progression, including hepatocellular carcinoma (HCC). The presence of tumor hemorrhage (TH) implies a fast-growing and worse tumor microenvironment. We examined a possible association betw...
作者:Ni Wang , Xiaohua Liang , Weijian Yu ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2018, Vol.50 (5), pp.1804-1814DOAJ
摘要:Background/Aims: MiR-19b has been reported to be involved in several malignancies, but its role in multiple myeloma (MM) is still unknown. The objective of this study was to explore the biological mechanism of miR-19b in the progression of MM. Methods: First, we performed re...
作者:Yingliang Wei , Yanfang Wang , Yutong Wang ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2017, Vol.42 (1), pp.319-332DOAJ
摘要:Background: Autophagy, a self-protective mechanism of chondrocytes, has become a promising target to impede the progress of osteoarthritis (OA). Autophagy is regulated by cytosolic Ca2+ activity and may thus be modified by the Ca2+ permeable transient receptor potential channel v...
作者:Liang Chang , Zhuang Hu , Zhenyu Zhou ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2018, Vol.48 (1), pp.16-28DOAJ
摘要:Background/Aims: Long non-coding RNAs (LncRNAs) have been validated to be pivotal mediators in multidrug resistance (MDR) of various cancers. This study aims to explore the roles and molecular mechanisms of linc00518 implicated in chemoresistance in breast cancer. Methods: Expres...
作者:Chuan-Zhong Huang , Ai-Min Huang , Jing-Feng Liu ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2018, Vol.47 (6), pp.2340-2349DOAJ
摘要:Background/Aims: Hepatocellular carcinoma (HCC) is a major threat to human health. The condition carries a high risk of death; 45% of new cases occur in China. Surgical resection is the first choice for treatment of HCC, but 30.9% of patients experience recurrence within 6 months...
作者:Cheng-kun Yang , Ting-dong Yu , Chuang-ye Han ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2017, Vol.42 (4), pp.1342-1357DOAJ
摘要:Background/Aims: Hepatocellular carcinoma (HCC) is a common malignant tumor with a high rate of recurrence. Immunohistochemical analysis of the marker of proliferation Ki-67 (MKI67) is used to assess proliferation activity of HCC The regulation of MKI67 expression remains unclear...
作者:Ning Wang , Lei Yang , Huixue Zhang ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2017, Vol.45 (1), pp.78-87DOAJ
摘要:Background/Aims: Previous studies have suggested that autophagy is activated in distinct cerebrovascular diseases, including stroke. However, the underlying regulatory mechanism of autophagy under stroke remained elusive. Accumulating evidence indicates that dysfunctions of ...
作者:Haijun Li , Fucheng He , Xin Zhao ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2017, Vol.44 (5), pp.2073-2089DOAJ
摘要:Background/Aims: The Hippo-Yap pathway is associated with tumor development and progression. However, little evidence is available concerning its role in cancer cell apoptosis and migration via mitochondrial homeostasis. Here, we identify mitochondrial fission as a regulator...

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