全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Ke Hengning , Zhang Jennifer Y , Akiyama Steven K ...
来源:[J].Cell Adhesion and Migration, 2010, Vol.5 (1), pp.6-10PubMed
摘要:In addition to its well-defined role as an antagonist in apoptosis, we propose that BCL2 may act as an intracellular suppressor of cell motility and adhesion under certain conditions. Our evidence shows that, when over-expressed in both cancer and non-cancer cells, BCL2 can form ...
作者:Fouchard Jonathan , Mitrossilis Démosthène , Asnacios Atef
来源:[J].Cell Adhesion and Migration, 2010, Vol.5 (1), pp.16-9PubMed
摘要:Cells sense the rigidity of their environment and respond to it. Most studies have been focused on the role of adhesion complexes in rigidity sensing. In particular, it has been clearly shown that proteins of the adhesion complexes were stretch-sensitive, and could thus trigger m...
作者:Colvin Richard A , Luster Andrew D
来源:[J].Cell Adhesion and Migration, 2010, Vol.5 (1), pp.56-8PubMed
摘要:Leukocyte chemotaxis plays an essential role in generating and delivering immune responses and is a critical component of inflammation. In order to identify novel genes and pathways important for regulating chemotaxis, we performed an RNAi-based screen and identified several gene...
作者:Cushman Ian , Casey Patrick J
来源:[J].Cell Adhesion and Migration, 2010, Vol.5 (1), pp.11-5PubMed
摘要:Numerous proteins involved in diverse aspects of cell biology undergo a process of post-translational modification termed prenylation. The prenylation pathway consists of three enzymatic steps, the final of which is methylation of the carboxyl-terminal prenylcysteine formed in th...
作者:Roth Lise
来源:[J].Cell Adhesion and Migration, 2010, Vol.5 (1), pp.1-3PubMed
摘要:Knocking down a human gene by RNA silencing has been the focus of a number of laboratories since the discovery of the RNAi mechanism more than 10 years ago. In their remarkable work, M. Davis and collaborators show for the first time the induction of an RNAi pathway in humans fol...
作者:Nagano Makoto , Hoshino Daisuke , Sakamoto Takeharu ...
来源:[J].Cell Adhesion and Migration, 2010, Vol.5 (1), pp.23-8PubMed
摘要:Adherent cells migrate on extracellular matrices (ECM) by repeated spreading and contraction of the cell body. Focal adhesions (FAs) play a major role in the adherence of cells to the ECM and in the generation of the cellular forces that maintain morphology and allow cells to mov...
作者:Forsprecher Jennifer , Wang Zhemeng , Goldberg Harvey A ...
来源:[J].Cell Adhesion and Migration, 2010, Vol.5 (1), pp.65-72PubMed
摘要:Tissue transglutaminase (TG2) is a widely distributed, protein-crosslinking enzyme having a prominent role in cell adhesion as a β1 integrin co-receptor for fibronectin. In bone and teeth, its substrates include the matricellular proteins osteopontin (OPN) and bone sialoprot...
作者:Pimton Pimchanok , Sarkar Saheli , Sheth Nidhi ...
来源:[J].Cell Adhesion and Migration, 2010, Vol.5 (1), pp.73-82PubMed
摘要:Embryonic stem (ES) cells have a broad potential application in regenerative medicine and can be differentiated into cells of all three germ layers. Adhesion of ES cells to extracellular matrix (ECM) proteins is essential for the differentiation pathway; Cell-ECM adhesion is...
作者:Klarlund Jes K , Block Ethan R
来源:[J].Cell Adhesion and Migration, 2010, Vol.5 (2), pp.106-10PubMed
摘要:One of the primary functions of any epithelium is to act as a barrier. To maintain integrity, epithelia migrate rapidly to cover wounds, and there is intense interest in understanding how wounds are detected. Numerous soluble factors are present in the wound environment and epith...
作者:Chacón Mariola R , Fazzari Pietro
来源:[J].Cell Adhesion and Migration, 2010, Vol.5 (1), pp.52-5PubMed
摘要:During the formation of neural circuitry, axons are known to be guided to their specific targets by a relatively small arsenal of guidance signals. However, the molecular integration of this guidance information inside the axonal growth cone (GC) is still baffling. Focal adhesion...

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