全部文献期刊会议图书|学者科研项目
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作者:Heeba Gehan H , El-Deen Reham , Abdel-Latif Rania G ...
来源:[J].Canadian journal of physiology and pharmacology, 2020
摘要:Nonalcoholic fatty liver disease (NAFLD) is an excessive accumulation of fats in the liver resulted in hepatic inflammation and fibrous tissue formation along with insulin resistance. This study was designed to investigate the possible protective effects of metformin alone a...
作者:Kilianova Zuzana , Ciznarova Natalia , Szmicsekova Kristina ...
来源:[J].Canadian journal of physiology and pharmacology, 2020
摘要:Acetylcholine-mediated vagal transmission as well as non-neuronal acetylcholine (ACh) release are considered cardioprotective in pathological situations with increased sympathetic drive such as ischemic-reperfusion and cardiac remodeling. ACh action is terminated by hydrolysis by...
作者:Hanikoglu Aysegul , Kucuksayan Ertan , Hanikoglu Ferhat ...
来源:[J].Canadian journal of physiology and pharmacology, 2020, Vol.98 (3), pp.131-138
摘要:Breast cancer is a worldwide commonly found malignancy in women and effective treatment is regarded as a huge clinical challenge even in the presence of several treatment options. Extensive literature is available demonstrating polyphenols as phytopharmaceutical anticancer a...
作者:Boardman Neoma T , Falck Aleksander Tank , Lund Trine ...
来源:[J].Canadian journal of physiology and pharmacology, 2020, Vol.98 (3), pp.139-146
摘要:Uric acid is a purine degradation product but also an important antioxidant and reactive oxygen species (ROS) scavenger. Experimental settings that mimic myocardial ischemia-reperfusion have not included uric acid despite that it is always present in human extracellular fluid and...
作者:Gumede Nontobeko M , Lembede Busisani W , Nkomozepi Pilani ...
来源:[J].Canadian journal of physiology and pharmacology, 2020, Vol.98 (1), pp.44-50
摘要:Fructose contributes to the development of nonalcoholic fatty liver disease (NAFLD). β-Sitosterol (Bst), a naturally occurring phytosterol, has antihyperlipidaemic and hepatoprotective properties. This study interrogated the potential protective effect of β-sitosterol agains...
作者:George Akash K , Majumder Avisek , Ice Hayley ...
来源:[J].Canadian journal of physiology and pharmacology, 2020, Vol.98 (2), pp.51-60
摘要:Homocysteine (Hcy), a sulfur-containing nonproteinogenic amino acid, is generated as a metabolic intermediate. Hcy constitutes an important part of the "1-carbon metabolism" during methionine turnover. Elevated levels of Hcy known as hyperhomocysteinemia (HHcy) results from vitam...
作者:Bin Jardan Yousef A , Abdussalam Ali , El-Kadi Ayman O S ...
来源:[J].Canadian journal of physiology and pharmacology, 2020, Vol.98 (3), pp.177-181
摘要:Dronedarone biodistribution in hyperlipidemia and dronedarone metabolism in hyperlipidemia or obesity were assessed. Male Sprague-Dawley rats were given either normal standard chow with water or various high-fat or high-carbohydrate diets for 14 weeks. There was also a nonobese h...
作者:Ilić Sonja , Stojiljković Nenad , Sokolović Dusan ...
来源:[J].Canadian journal of physiology and pharmacology, 2020, pp.1-7
摘要:Since cisplatin-induced nephrotoxicity has very important clinical consequences, the purpose of this study was to determine the potential protective effect of aminoguanidine on the acute kidney injury caused by cisplatin. Experiments were done on 40 Wistar rats divided into four ...

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