全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Monica E. Reyes , Takeo Fujii , Daniel Branstetter ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2017, Vol.164 (1), pp.57-67Springer
摘要:As clinical studies have correlated RANK expression levels with survival in breast cancer, and that RANK signaling is dependent on its cognate ligand RANKL, we hypothesized that dual protein expression further stratifies the poor outcome in TNBC.
作者:Muhammad Asaduzzaman , Stephanie Constantinou , Haoxiang Min ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2017, Vol.163 (3), pp.461-474Springer
摘要:We have previously described a novel pathway controlling drug resistance, epithelial-to-mesenchymal transition (EMT) and stemness in breast cancer cells. Upstream in the pathway, three miRs (miR-106b, miR-93 and miR-25) target EP300, a transcriptional activator of E-cadherin. Upr...
作者:Dorota Kwapisz
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2017, Vol.166 (1), pp.41-54Springer
摘要:The cyclin D-cyclin dependent kinase (CDK) 4/6-inhibitor of CDK4 (INK4)-retinoblastoma (Rb) pathway plays a crucial role in cell cycle progression and its dysregulation is an important contributor to endocrine therapy resistance. CDK4/6 inhibitors trigger cell cycle arrest in Rb ...
作者:Hope S. Rugo , Olivier Trédan , Jungsil Ro ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2017, Vol.165 (3), pp.601-609Springer
摘要:To evaluate whether adding humanized monoclonal insulin growth factor-1 receptor (IGF-1R) antibody (dalotuzumab) to mammalian target of rapamycin (mTOR) inhibitor (ridaforolimus) plus aromatase inhibitor (exemestane) improves outcomes in patients with estrogen receptor (ER)-posit...
作者:Xiaohong R. Yang , Beena C. R. Devi , Hyuna Sung ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2017, Vol.165 (3), pp.687-697Springer
摘要:To characterize the spectrum of germline mutations in BRCA1 , BRCA2 , and PALB2 in population-based unselected breast cancer cases in an Asian population.
作者:Elena V. Preobrazhenskaya , Ilya V. Bizin , Ekatherina Sh. Kuligina ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2017, Vol.165 (3), pp.765-770Springer
摘要:Large genomic rearrangements (LGRs) constitute a significant share of pathogenic BRCA1 mutations. Multiplex ligation-dependent probe amplification (MLPA) is a leading method for LGR detection; however, it is entirely based on the use of commercial kits, includes relatively time-c...
作者:Susan T. Vadaparampil , Juliette Christie , Kristine A. Donovan ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2017, Vol.163 (2), pp.331-342Springer
摘要:Black women are more likely to develop early-onset (≤50 years) breast cancer (BC) and have the lowest five-year, cause-specific survival rate of any United States (U.S.) racial or ethnic group. These disparities can be attributed partially to the higher rate of triple-negati...
作者:Tae In Yoon , Ui-Kang Hwang , Eui Tae Kim ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2017, Vol.165 (2), pp.311-320Springer
摘要:We investigated the oncologic outcomes by intrinsic subtype and age in young breast cancer patients and whether survival differences were related to treatment changes over time.
作者:Yusuke Suzuki , Hiroko Tsunoda , Takeshi Kimura ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2017, Vol.166 (3), pp.919-925Springer
摘要:We investigated the association between breast cancer incidence and obesity among Asian women.

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