全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Lou Wenjia , Reynolds Christian A , Li Yiran ...
来源:[J].Biochimica et biophysica acta. Molecular and cell biology of lipids(IF 4.134), 2018, Vol.1863 (8), pp.857-865PubMed
摘要:Barth syndrome (BTHS) is an X-linked genetic disorder resulting from mutations in the tafazzin gene (TAZ), which encodes the transacylase that remodels the mitochondrial phospholipid cardiolipin (CL). While most BTHS patients exhibit pronounced skeletal myopathy, the mechanisms l...
作者:Ulicna Livia , Kalendova Alzbeta , Kalasova Ilona ...
来源:[J].Biochimica et biophysica acta. Molecular and cell biology of lipids(IF 4.134), 2018, Vol.1863 (3), pp.266-275PubMed
摘要:Phosphoinositides are present in the plasma membrane, cytoplasm and inside the cell nucleus. Here we identify phosphatidylinositol-4,5-bisphosphate (PIP2) as a regulator of rRNA genes transcription at the epigenetic level. We show that PIP2 directly interacts with histone lysine ...
作者:Kang Saeromi , Huang Jin , Lee Bo-Kyung ...
来源:[J].Biochimica et biophysica acta. Molecular and cell biology of lipids(IF 4.134), 2018, Vol.1863 (2), pp.105-116PubMed
摘要:Protective effect of omega-3 polyunsaturated fatty acids (n-3 PUFA) on non-alcoholic fatty liver disease has been demonstrated. FFA4 (also known as GPR120; a G protein-coupled receptor) has been suggested to be a target of n-3 PUFA. FFA4 expression in hepatocytes has also been re...
作者:Sæle Øystein , Rød Kari Elin L , Quinlivan Vanessa H ...
来源:[J].Biochimica et biophysica acta. Molecular and cell biology of lipids(IF 4.134), 2018, Vol.1863 (9), pp.948-957PubMed
摘要:The zebrafish larva is a powerful tool for the study of dietary triglyceride (TG) digestion and how fatty acids (FA) derived from dietary lipids are absorbed, metabolized and distributed to the body. While fluorescent FA analogues have enabled visualization of FA metabolism, meth...
作者:Zhang Meng , Zhai Xiaobo , Li Jinping ...
来源:[J].Biochimica et biophysica acta. Molecular and cell biology of lipids(IF 4.134), 2018, Vol.1863 (9), pp.1082-1094PubMed
摘要:Human phospholipid transfer protein (PLTP) mediates the transfer of phospholipids among atheroprotective high-density lipoproteins (HDL) and atherogenic low-density lipoproteins (LDL) by an unknown mechanism. Delineating this mechanism would represent the first step towards under...
作者:Liu Mingxia , Chung Soonkyu , Shelness Gregory S ...
来源:[J].Biochimica et biophysica acta. Molecular and cell biology of lipids(IF 4.134), 2017, Vol.1862 (10 Pt A), pp.1035-1043PubMed
摘要:ATP binding cassette transporter A1 (ABCA1) is a membrane transporter that facilitates nascent HDL formation. Tangier disease subjects with complete ABCA1 deficiency have <5% of normal levels of plasma HDL, elevated triglycerides (TGs), and defective vesicular trafficking in fibr...
作者:Arhab Yani , Abousalham Abdelkarim , Noiriel Alexandre
来源:[J].Biochimica et biophysica acta. Molecular and cell biology of lipids, 2019PubMed
摘要:Phospholipase D (PLD) is a key enzyme involved in numerous processes in all living organisms. Hydrolysis of phospholipids by PLD allows the release of phosphatidic acid which is a crucial intermediate of multiple pathways and signaling reactions, including tumorigenesis in m...
作者:Leopold Christina , Duta-Mare Madalina , Sachdev Vinay ...
来源:[J].Biochimica et biophysica acta. Molecular and cell biology of lipids, 2019PubMed
摘要:Lysosomal acid lipase (LAL) hydrolyzes cholesteryl esters (CE) and triglycerides (TG) to generate fatty acids (FA) and cholesterol. LAL deficiency (LAL-D) in both humans and mice leads to hepatomegaly, hypercholesterolemia, and shortened life span. Despite its essential role in l...
作者:Sukhorukov Vasily , Gudelj Ivan , Pučić-Baković Maja ...
来源:[J].Biochimica et biophysica acta. Molecular and cell biology of lipids, 2019PubMed
摘要:AIMS(#br)Human plasma lipoproteins are known to contain various glycan structures whose composition and functional importance are starting to be recognized. We assessed N-glycosylation of human plasma HDL and LDL and the role of their glycomes in cellular cholesterol metabolism.(...
作者:Gürtler Sarah , Wolke Carmen , Otto Oliver ...
来源:[J].Biochimica et biophysica acta. Molecular and cell biology of lipids, 2019PubMed
摘要:The mitochondrial phospholipid cardiolipin (CL) has been implicated with mitochondrial morphology, function and, more recently, with cellular proliferation. Tafazzin, an acyltransferase with key functions in CL remodeling determining actual CL composition, affects mitochondrial o...

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