全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Patrick T. Kang , Chwen-Lih Chen , Paul Lin ...
来源:[J].Basic Research in Cardiology(IF 5.904), 2017, Vol.112 (4)Springer
摘要:The mitochondrial electrochemical gradient (Δ p ), which comprises the pH gradient (ΔpH) and the membrane potential (ΔΨ), is crucial in controlling energy transduction. During myocardial ischemia and reperfusion (IR), mitochondrial dysfunction mediates superoxide (...
作者:T. R. G. Stams , A. Dunnink , W. M. van Everdingen ...
来源:[J].Basic Research in Cardiology(IF 5.904), 2017, Vol.112 (4)Springer
摘要:In the chronic complete atrioventricular (AV) block dog (CAVB) model, both bradycardia and altered ventricular activation due to the uncontrolled idioventricular rhythm contribute to ventricular remodeling and the enhanced susceptibility to Torsade de Pointes (TdP) arrhythmi...
作者:André Uitterdijk , Tirza Springeling , Kevin C. M. Hermans ...
来源:[J].Basic Research in Cardiology(IF 5.904), 2017, Vol.112 (3)Springer
摘要:Despite early revascularization, remodeling and dysfunction of the left ventricle (LV) after acute myocardial infarction (AMI) remain important therapeutic targets. Intermittent pacing therapy (IPT) of the LV can limit infarct size, when applied during early reperfusion. How...
作者:Laura Padrón-Barthe , Fernando Domínguez , Pablo Garcia-Pavia ...
来源:[J].Basic Research in Cardiology(IF 5.904), 2017, Vol.112 (5)Springer
摘要:Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare genetically-determined cardiac heart muscle disorder characterized by fibro-fatty replacement of the myocardium that results in heart failure and sudden cardiac death (SCD), predominantly in young males. The disease...
作者:Teresa A. Zimmers , Yanling Jiang , Meijing Wang ...
来源:[J].Basic Research in Cardiology(IF 5.904), 2017, Vol.112 (4)Springer
摘要:Growth differentiation factor 11 (GDF11), a TGF-beta superfamily member, is highly homologous to myostatin and essential for embryonic patterning and organogenesis. Reports of GDF11 effects on adult tissues are conflicting, with some describing anti-aging and pro-regenerativ...
作者:Klaus-Dieter Schlüter , Annemarie Wolf , Martin Weber ...
来源:[J].Basic Research in Cardiology(IF 5.904), 2017, Vol.112 (6)Springer
摘要:Recent studies have documented that oxidized low-density lipoprotein cholesterol (oxLDL) levels directly impact myocardial structure and function. However, the molecular mechanisms by which oxLDL affects cardiac myocytes are not well established. We addressed the question whether...
作者:Olga Eleftheriadou , Andrii Boguslavskyi , Michael R. Longman ...
来源:[J].Basic Research in Cardiology(IF 5.904), 2017, Vol.112 (4)Springer
摘要:Cardiac physiology and hypertrophy are regulated by the phosphorylation status of many proteins, which is partly controlled by a poorly defined type 2A protein phosphatase-alpha4 intracellular signalling axis. Quantitative PCR analysis revealed that mRNA levels of the type 2...

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