全部文献期刊会议图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Maolan Wu , Xiangrong Zheng , Xia Wang ...
来源:[J].BMC Medical Genomics(IF 3.466), 2020, Vol.13 (2), pp.383-385Springer
摘要:Abstract(#br)Background(#br)Chromosome deletions of the long arm of chromosome 4 in 4q syndrome are characterized by mild facial and digital dysmorphism, developmental delay, growth retardation, and skeletal and cardiac anomalies, which is regarded as an autism spectrum diso...
作者:Sofia Dória , Daniela Alves , Maria João Pinho ...
来源:[J].BMC Medical Genomics(IF 3.466), 2020, Vol.13 (9), pp.264-268Springer
摘要:Abstract(#br)Background(#br)12q14 microdeletion syndrome is characterized by low birth weight and failure to thrive, proportionate short stature and developmental delay. The opposite syndrome (microduplication) has not yet been characterized. Our main objective is the recognition...
作者:Md. Altaf-Ul-Amin , Mohammad Bozlul Karim , Pingzhao Hu ...
来源:[J].BMC Medical Genomics(IF 3.466), 2020, Vol.13 (5), pp.4653-62Springer
摘要:Abstract(#br)Background(#br)Multidimensional data mining from an integrated environment of different data sources is frequently performed in computational system biology. The molecular mechanism from the analysis of a complex network of gene-miRNA can aid to diagnosis and treatme...
作者:Li Gao , Shi-bai Yan , Jie Yang ...
来源:[J].BMC Medical Genomics(IF 3.466), 2020, Vol.13 (1), pp.252-271Springer
摘要:Abstract(#br)Background(#br)MiR-182-5p, a cancer-related microRNA (miRNA), modulates tumorigenesis and patient outcomes in various human malignances. This study interroted the clinicopathological significance and molecular mechanisms of miR-182-5p in non-small cell lung cancer (N...
作者:Ieva Rauluseviciute , Finn Drabløs , Morten Beck Rye
来源:[J].BMC Medical Genomics(IF 3.466), 2020, Vol.13 (3), pp.E359-E386Springer
摘要:Abstract(#br)Background(#br)Prostate cancer (PCa) has the highest incidence rates of cancers in men in western countries. Unlike several other types of cancer, PCa has few genetic drivers, which has led researchers to look for additional epigenetic and transcriptomic contrib...
作者:Chai-Jin Lee , Hongryul Ahn , Dabin Jeong ...
来源:[J].BMC Medical Genomics(IF 3.466), 2020, Vol.13 (4), pp.57-66Springer
摘要:Abstract(#br)Background(#br)In cancer, mutations of DNA methylation modification genes have crucial roles for epigenetic modifications genome-wide, which lead to the activation or suppression of important genes including tumor suppressor genes. Mutations on the epigenetic modifie...
作者:Haohan Wang , Michael M. Vanyukov , Eric P. Xing ...
来源:[J].BMC Medical Genomics(IF 3.466), 2020, Vol.13 (5), pp.747-53Springer
摘要:Abstract(#br)Background(#br)The current understanding of the genetic basis of complex human diseases is that they are caused and affected by many common and rare genetic variants. A considerable number of the disease-associated variants have been identified by Genome Wide As...
作者:Justyna A. Karolak , Tomasz Gambin , Engela M. Honey ...
来源:[J].BMC Medical Genomics(IF 3.466), 2020, Vol.13 (14), pp.74-82Springer
摘要:Abstract(#br)Background(#br)Application of whole genome sequencing (WGS) enables identification of non-coding variants that play a phenotype-modifying role and are undetectable by exome sequencing. Recently, non-coding regulatory single nucleotide variants (SNVs) have been report...
作者:Adham Beykikhoshk , Thomas P. Quinn , Samuel C. Lee ...
来源:[J].BMC Medical Genomics(IF 3.466), 2020, Vol.13 (43), pp.531-7Springer
摘要:Abstract(#br)Background(#br)Breast cancer is a collection of multiple tissue pathologies, each with a distinct molecular signature that correlates with patient prognosis and response to therapy. Accurately differentiating between breast cancer sub-types is an important part of cl...
作者:Nerissa L. Hearn , Christine L. Chiu , Joanne M. Lind
来源:[J].BMC Medical Genomics(IF 3.466), 2020, Vol.13 (1), pp.1099-1106Springer
摘要:Abstract(#br)Background(#br)Coeliac disease (CD) is a autoimmune disease characterised by mucosal inflammation in the small intestine in response to dietary gluten. Genetic factors play a key role with CD individuals carrying either the HLA-DQ2 or HLA-DQ8 haplotype, however these...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×