全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Noriyuki Takahashi , Takayuki Saitoh , Nanami Gotoh ...
来源:[J].BMC Immunology(IF 2.61), 2017, Vol.18 (1)Springer
摘要:T-helper cell type 1 (Th1) polarization in chronic immune thrombocytopenia (cITP) has been reported at the protein and mRNA levels. We evaluated the impact of Th1/Th2 cytokine and cytokine receptor functional polymorphisms on both susceptibility to, and severity of, cITP. We...
作者:Shinji Watanabe , Takahisa Gono , Kumiko Nishina ...
来源:[J].BMC Immunology(IF 2.61), 2017, Vol.18 (1)Springer
摘要:Some patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) also have positivity of rheumatoid factor (RF). However, the clinical significance of this occurrence remains unknown in AAV patients. The aim of this study was to clarify an association bet...
作者:James K. Peterson , Alison M. Kesson , Nicholas J. C. King
来源:[J].BMC Immunology(IF 2.61), 2017, Vol.18 (1)Springer
摘要:In this work, we develop a theoretical model of an auto immune response. This is based on modifications of standard second messenger trigger models using both signalling pathways and diffusion and a macro level dynamic systems approximation to the response of a triggering agent s...
作者:Marian-Christopher Pott , Natalie Frede , Jennifer Wanders ...
来源:[J].BMC Immunology(IF 2.61), 2017, Vol.18 (1)Springer
摘要:The ability of anti-cytokine antibodies to play a disease-causing role in the pathogenesis of immunodeficiencies is widely accepted. The aim of this study was to investigate whether autoantibodies against BAFF (important B cell survival signal), APRIL (important plasma cell survi...
作者:Guoying Ni , Zaowen Liao , Shu Chen ...
来源:[J].BMC Immunology(IF 2.61), 2017, Vol.18 (1)Springer
摘要:Cancer therapeutic vaccine induced cytotoxic T cell (CTL) responses are pivotal for the killing of tumour cells. Blocking interleukin 10 (IL-10) signalling at the time of immunization increases vaccine induced CTL responses and improves prevention of tumour growth in animal model...
作者:Unni Gopinathan , Reidun Øvstebø , Berit Sletbakk Brusletto ...
来源:[J].BMC Immunology(IF 2.61), 2017, Vol.18 (1)Springer
摘要:Biological interpretation of DNA microarray data may differ depending on underlying assumptions and statistical tests of bioinformatics tools used. We used Gene Set Enrichment Analysis (GSEA) and Ingenuity Pathway Analysis (IPA) to analyze previously generated DNA microarray...
作者:Yan Liang , Xiaoyan Zhang , Xuejuan Bai ...
来源:[J].BMC Immunology(IF 2.61), 2017, Vol.18 (1)Springer
摘要:Tuberculosis (TB) is a major global public health problem. New treatment methods on TB are urgently demanded. In this study, Mycobacterium tuberculosis (MTB) rv2190c DNA vaccine was prepared and its immunogenicity and therapeutic effects were evaluated.
作者:Olivier Garraud , Wael N. Hozzein , Gamal Badr
来源:[J].BMC Immunology(IF 2.61), 2017, Vol.18 (1)Springer
摘要:There is now good evidence that cytokines and growth factors are key factors in tissue repair and often exert anti-infective activities. However, engineering such factors for global use, even in the most remote places, is not realistic. Instead, we propose to examine how suc...
作者:Akane Tanaka , Joyce To , Bronwyn O’Brien ...
来源:[J].BMC Immunology(IF 2.61), 2017, Vol.18 (1)Springer
摘要:Macrophages are key players in the initiation, perpetuation and regulation of both innate and adaptive immune responses. They largely perform these roles through modulation of the expression of genes, especially those encoding cytokines. Murine bone marrow derived macrophage...
作者:Kurt Hanevik , Einar Kristoffersen , Kristine Mørch ...
来源:[J].BMC Immunology(IF 2.61), 2017, Vol.18 (1)Springer
摘要:The role of pathogen specific cellular immune responses against the eliciting pathogen in development of post-infectious chronic fatigue syndrome (PI-CFS) is not known and such studies are difficult to perform. The aim of this study was to evaluate specific anti- Giardia cellular...

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