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作者:Babic Julien , Griscom Laurent , Cramer Jeremy ...
来源:[J].BMC cell biology(IF 2.808), 2018, Vol.19 (1), pp.8
摘要:BACKGROUND(#br)Real-time monitoring of cellular responses to dynamic changes in their environment or to specific treatments has become central to cell biology. However, when coupled to live-cell imaging, such strategies are difficult to implement with precision and high time reso...
作者:Wu Hao , Yin Zhanhai , Wang Ling ...
来源:[J].BMC cell biology(IF 2.808), 2017, Vol.18 (1), pp.29
摘要:BACKGROUND(#br)Cartilage degradation is the significant pathological process in osteoarthritis (OA). Inflammatory cytokines, such as interleukin-1β (IL-1β), activate various downstream mediators contributing to OA pathology. Recently, stem cell-based cartilage repair emerges...
作者:Nichols Anne E C , Settlage Robert E , Werre Stephen R ...
来源:[J].BMC cell biology(IF 2.808), 2018, Vol.19 (1), pp.14
摘要:BACKGROUND(#br)Tendinopathies are common and difficult to resolve due to the formation of scar tissue that reduces the mechanical integrity of the tissue, leading to frequent reinjury. Tenocytes respond to both excessive loading and unloading by producing pro-inflammatory mediato...
作者:Witt R , Weigand A , Boos A M ...
来源:[J].BMC cell biology(IF 2.808), 2017, Vol.18 (1), pp.15
摘要:BACKGROUND(#br)Volumetric muscle loss caused by trauma or after tumour surgery exceeds the natural regeneration capacity of skeletal muscle. Hence, the future goal of tissue engineering (TE) is the replacement and repair of lost muscle tissue by newly generating skeletal mus...
作者:Smith Elizabeth R , Meng Yue , Moore Robert ...
来源:[J].BMC cell biology(IF 2.808), 2017, Vol.18 (1), pp.8
摘要:BACKGROUND(#br)Nuclear size and shape are specific to a cell type, function, and location, and can serve as indicators of disease and development. We previously found that lamin A/C and associated nuclear envelope structural proteins were upregulated when murine embryonic stem (E...
作者:Lewis Tylor R , Kundinger Sean R , Link Brian A ...
来源:[J].BMC cell biology(IF 2.808), 2018, Vol.19 (1), pp.25
摘要:BACKGROUND(#br)KIF17, a kinesin-2 motor that functions in intraflagellar transport, can regulate the onset of photoreceptor outer segment development. However, the function of KIF17 in a mature photoreceptor remains unclear. Additionally, the ciliary localization of KIF17 is regu...
作者:Berthoud Viviana M , Ngezahayo Anaclet
来源:[J].BMC cell biology(IF 2.808), 2017, Vol.18 (Suppl 1), pp.6
摘要:The lens is an avascular organ composed of an anterior epithelial cell layer and fiber cells that form the bulk of the organ. The lens expresses connexin43 (Cx43), connexin46 (Cx46) and connexin50 (Cx50). Epithelial Cx50 has critical roles in cell proliferation and differentiatio...
作者:Shipman Emma N , Jones Kiersun , Jenkinson Cory B ...
来源:[J].BMC cell biology(IF 2.808), 2017, Vol.18 (1), pp.11
摘要:BACKGROUND(#br)To cause an economically important blast disease on rice, the filamentous fungus Magnaporthe oryzae forms a specialized infection structure, called an appressorium, to penetrate host cells. Once inside host cells, the fungus produces a filamentous primary hyph...
作者:van Unen J , Botman D , Yin T ...
来源:[J].BMC cell biology(IF 2.808), 2018, Vol.19 (1), pp.6
摘要:BACKGROUND(#br)Rho guanine exchange factors (RhoGEFs) control cellular processes such as migration, adhesion and proliferation. Alternative splicing of the RhoGEF Trio produces TGAT. The RhoGEF TGAT is an oncoprotein with constitutive RhoGEF activity. We investigated whether...
作者:Chen Nan , He Sai , Geng Jie ...
来源:[J].BMC cell biology(IF 2.808), 2018, Vol.19 (1), pp.5
摘要:BACKGROUND(#br)Contactin1 (CNTN1) has been shown to play an important role in the invasion and metastasis of several tumors; however, the role of CNTN1 in breast cancer has not been fully studied. The purpose of this study is to investigate the role of CNTN1 in regulating tumor g...

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