全部文献期刊会议图书|学者科研项目
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作者:Robert Esch , Rainer Merkl
来源:[J].BMC Bioinformatics(IF 3.024), 2020, Vol.21 (1), pp.318-356Springer
摘要:Abstract(#br)Background(#br)The order of genes in bacterial genomes is not random; for example, the products of genes belonging to an operon work together in the same pathway. The cotranslational assembly of protein complexes is deemed to conserve genomic neighborhoods even ...
作者:Jianbo Zhang , Dilip R. Panthee
来源:[J].BMC Bioinformatics(IF 3.024), 2020, Vol.21 (2), pp.6553-6568Springer
摘要:Abstract(#br)Background(#br)Bulked segregant analysis (BSA), coupled with next-generation sequencing, allows the rapid identification of both qualitative and quantitative trait loci (QTL), and this technique is referred to as BSA-Seq here. The current SNP index method and G-...
作者:Feixiao Long
来源:[J].BMC Bioinformatics(IF 3.024), 2020, Vol.21 (1), pp.115-125Springer
摘要:Abstract(#br)Background(#br)Cell nuclei segmentation is a fundamental task in microscopy image analysis, based on which multiple biological related analysis can be performed. Although deep learning (DL) based techniques have achieved state-of-the-art performances in image segment...
作者:Eugene Lin , Sudipto Mukherjee , Sreeram Kannan
来源:[J].BMC Bioinformatics(IF 3.024), 2020, Vol.21 (8), pp.1138-1142Springer
摘要:Abstract(#br)Background(#br)Single-cell RNA sequencing (scRNA-seq) is an emerging technology that can assess the function of an individual cell and cell-to-cell variability at the single cell level in an unbiased manner. Dimensionality reduction is an essential first step in down...
作者:Nicholas Stoler , Barbara Arbeithuber , Gundula Povysil ...
来源:[J].BMC Bioinformatics(IF 3.024), 2020, Vol.21 (1), pp.R25-865Springer
摘要:Abstract(#br)Background(#br)Duplex sequencing is the most accurate approach for identification of sequence variants present at very low frequencies. Its power comes from pooling together multiple descendants of both strands of original DNA molecules, which allows distinguish...
作者:S. K. Hong , Jae-Gil Lee
来源:[J].BMC Bioinformatics(IF 3.024), 2020, Vol.21 (10), pp.15-52Springer
摘要:Abstract(#br)Background(#br)Biomedical named-entity recognition (BioNER) is widely modeled with conditional random fields (CRF) by regarding it as a sequence labeling problem. The CRF-based methods yield structured outputs of labels by imposing connectivity between the labels. Re...
作者:Jia Li , Yue Yin , Mutian Zhang ...
来源:[J].BMC Bioinformatics(IF 3.024), 2020, Vol.21 (W1), pp.487-500Springer
摘要:Abstract(#br)Background(#br)Epigenetic regulation is essential in regulating gene expression across a variety of biological processes. Many high-throughput sequencing technologies have been widely used to generate epigenetic data, such as histone modification, transcription ...
作者:Defne Surujon , Tim van Opijnen
来源:[J].BMC Bioinformatics(IF 3.024), 2020, Vol.21 (2), pp.613-619Springer
摘要:Abstract(#br)Background(#br)Omics-profiling is a collection of increasingly prominent approaches that result in large-scale biological datasets, for instance capturing an organism’s behavior and response in an environment. It can be daunting to manually analyze and interpret...
作者:Sinead E Morris , Luise Dziobek-Garrett , Andrew J Yates ...
来源:[J].BMC Bioinformatics(IF 3.024), 2020, Vol.21 (21), pp.1736-1788Springer
摘要:Abstract(#br)Background(#br)HIV/AIDS is responsible for the deaths of one million people every year. Although mathematical modeling has provided many insights into the dynamics of HIV infection, there is still a lack of accessible tools for researchers unfamiliar with modeling te...
作者:Lucile Mégret , Satish Sasidharan Nair , Julia Dancourt ...
来源:[J].BMC Bioinformatics(IF 3.024), 2020, Vol.21 (1), pp.623-633Springer
摘要:Abstract(#br)Background(#br)MicroRNA (miRNA) regulation is associated with several diseases, including neurodegenerative diseases. Several approaches can be used for modeling miRNA regulation. However, their precision may be limited for analyzing multidimensional data. Here,...

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