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作者:Adam J. Wells , Adam R. Jajtner , Alyssa N. Varanoske ...
来源:[J].Amino Acids(IF 3.914), 2017, Vol.49 (8), pp.1415-1426
摘要:Attenuating TNFα/TNFr1 signaling in monocytes has been proposed as a means of mitigating inflammation. The purpose of this study was to examine the effects of a milk protein supplement on TNFα and monocyte TNFr1 expression. Ten resistance-trained men (24.7 ± 3.4 years; 90.1 ...
作者:Jason M. Cholewa , Dominique Dardevet , Fernanda Lima-Soares ...
来源:[J].Amino Acids(IF 3.914), 2017, Vol.49 (5), pp.811-820
摘要:Dietary proteins/essential amino acids (EAAs) are nutrients with anabolic properties that may increase muscle mass or attenuate muscle loss during immobilization and aging via the stimulation of muscle protein synthesis (MPS). An EAA’s anabolic threshold, capable to maximize...
作者:Woo Seok Yang , Seung-Gu Yeo , Sungjae Yang ...
来源:[J].Amino Acids(IF 3.914), 2017, Vol.49 (9), pp.1469-1485
摘要:Among the enzymes involved in the post-translational modification of Ras, isoprenyl carboxyl methyltransferase (ICMT) has been explored by a number of researchers as a significant enzyme controlling the activation of Ras. Indeed, inhibition of ICMT exhibited promising anti-cancer...
作者:Liuqin He , Xihong Zhou , Niu Huang ...
来源:[J].Amino Acids(IF 3.914), 2017, Vol.49 (12), pp.1999-2007
摘要:Pregnane X receptor (PXR, NR1I2), a member of the nuclear receptor superfamily, is a crucial regulator of nutrient metabolism and metabolic detoxification such as metabolic syndrome, xenobiotic metabolism, inflammatory responses, glucose, cholesterol and lipid metabolism, and end...
作者:Vijay Joshi , Alisdair R. Fernie
来源:[J].Amino Acids(IF 3.914), 2017, Vol.49 (9), pp.1543-1559
摘要:Citrulline was chemically isolated more than 100 years ago and is ubiquitous in animals, plants, bacteria, and fungi. Most of the research on plant citrulline metabolism and transport has been carried out in Arabidopsis thaliana and the Cucurbitaceae family, particularly in water...
作者:Yibing Wang , Xiaohan Song , Jiang Wang ...
来源:[J].Amino Acids(IF 3.914), 2017, Vol.49 (9), pp.1487-1520
摘要:This review article critically discusses examples of asymmetric synthesis of tailor-made α-amino acids via homologation of Ni(II) complexes of glycine and alanine Schiff bases, reported in the literature from 2013 through the end of 2016. Where it is possible, reaction mecha...
作者:Eduardo F. C. Junior , Carlos F. R. C. Guimarães , Lucas L. Franco ...
来源:[J].Amino Acids(IF 3.914), 2017, Vol.49 (8), pp.1389-1400
摘要:This work proposes a strategy that uses solid-phase peptide synthesis associated with copper(I)-catalyzed azide alkyne cycloaddition reaction to promote the glycosylation of an antimicrobial peptide (HSP1) containing a carboxyamidated C -terminus (HSP1-NH2). Two g...
作者:Tarique Hussain , Bie Tan , Wenkai Ren ...
来源:[J].Amino Acids(IF 3.914), 2017, Vol.49 (9), pp.1457-1468
摘要:Polyamines are naturally occurring aliphatic compounds, particularly essential elements for biological functions. These compounds play a central role in regulating molecular pathways which are responsible for cellular proliferation, growth, and differentiation. Importantly, exces...
作者:Anthony Bougas , Ioannis A. Vlachogiannis , Dimitrios Gatos ...
来源:[J].Amino Acids(IF 3.914), 2017, Vol.49 (5), pp.995-1004
摘要:Chloramphenicol peptides were recently established as useful tools for probing nascent polypeptide chain interaction with the ribosome, either biochemically, or structurally. Here, we present a new 10mer chloramphenicol peptide, which exerts a dual inhibition effect on the riboso...
作者:Cristiano Bolchi , Francesco Bavo , Marco Pallavicini
来源:[J].Amino Acids(IF 3.914), 2017, Vol.49 (5), pp.965-974
摘要:The enantiomers of amino acid benzyl esters are very important synthetic intermediates. Many of them are currently prepared by treatment with benzyl alcohol and p -toluenesulfonic acid in refluxing benzene or carbon tetrachloride, to azeotropically remove water, and then pre...

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