全部文献期刊会议图书|学者科研项目
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作者:Guihua Liu , Rongpei Wu , Bin Yang ...
来源:[J].Acta Biomaterialia(IF 5.093), 2020
摘要:Abstract(#br)Traditional cell therapy technology relies on the maximum expansion of primary stem cells in vitro , through multiple passages and potential differentiation protocols, in order to generate the abundance of cells needed prior to transplantation in vivo . Implanta...
作者:Keni Yang , Bárbara Mesquita , Peter Horvatovich ...
来源:[J].Acta Biomaterialia(IF 5.093), 2020
摘要:Abstract(#br)Nano-sized objects such as liposomes are modified by adsorption of biomolecules in biological fluids. The resulting corona critically changes nanoparticle behavior at cellular level. A better control of corona composition could allow to modulate uptake by cells. With...
作者:Justine R. Yu , Miriam Janssen , Barry J. Liang ...
来源:[J].Acta Biomaterialia(IF 5.093), 2020
摘要:Abstract(#br)Chronic, non-healing skin and soft tissue wounds are susceptible to infection, difficult to treat clinically, and can severely reduce a patient's quality of life. A key aspect of this issue is the impaired recruitment of mesenchymal stem cells (MSCs), which secr...
作者:Ting Yang , Ziling Wu , Hongshun Chen ...
来源:[J].Acta Biomaterialia(IF 5.093), 2020
摘要:Abstract(#br)The mineralized skeletons of echinoderms are characterized by their complex, open-cell porous microstructure (also known as stereom), which exhibits vast variations in pore sizes, branch morphology, and three-dimensional (3D) organization patterns among differen...
作者:Thomas Später , Anne L. Tobias , Maximilian M. Menger ...
来源:[J].Acta Biomaterialia(IF 5.093), 2020
摘要:Abstract(#br)Porous polyethylene (pPE) is a commonly used biomaterial in craniofacial reconstructive surgery. However, implant failure due to insufficient vascularization represents a major issue. To overcome this problem, we herein introduce an effective strategy to improve...
作者:Thomas D. Michl , Ben Hibbs , Lauren Hyde ...
来源:[J].Acta Biomaterialia(IF 5.093), 2020
摘要:Abstract(#br)Amphiphilic polymers bearing cationic moieties are an emerging alternative to traditional antibiotics given their broad-spectrum activity and low susceptibility to the development of resistance. To date, however, much remains unclear regarding their mechanism of acti...
作者:Ziying Li , Lisheng Zhu , Weiqun Liu ...
来源:[J].Acta Biomaterialia(IF 5.093), 2020
摘要:Abstract(#br)Combination therapy offers promising opportunities for treating advanced non-small cell lung cancer (NSCLC). Here, we established a chitosan-based nanocomplex CE7Q/CQ/S to deliver molecular-targeted drug erlotinib (Er), Survivin shRNA-expressing plasmid (SV), and pho...
作者:Amrita Pal , Cameron I. Smith , Joanna Palade ...
来源:[J].Acta Biomaterialia(IF 5.093), 2020
摘要:Abstract(#br)Injectable hydrogels provide a powerful and non-invasive approach for numerous applications in cell transplantation, growth factor delivery, tissue regeneration and so forth. The properties of injectable hydrogels should be well-tuned for specific applications, where...
作者:Wenkai Wang , Rui Zuo , Haixia Long ...
来源:[J].Acta Biomaterialia(IF 5.093), 2020
摘要:Abstract(#br)The periosteum plays a critical role in bone formation and defect reconstruction. The concept of tissue engineering in the periosteum has been suggested to solve the clinical problems related to bone defect repair. Insertion of polymethyl methacrylate (PMMA) bon...
作者:Sean J. Cone , Andrew T. Fuquay , Justin M. Litofsky ...
来源:[J].Acta Biomaterialia(IF 5.093), 2020
摘要:Abstract(#br)Proper wound healing necessitates both coagulation (the formation of a blood clot) and fibrinolysis (the dissolution of a blood clot). A thrombus resistant to clot dissolution can obstruct blood flow, leading to vascular pathologies. This study seeks to understand th...

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