全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Sander B. Frank , Veronique V. Schulz , Cindy K. Miranti
来源:[J].BMC Biotechnology(IF 2.165), 2017, Vol.17 (1)Springer
摘要:... Lentiviral vectors can be used to deliver shRNAs, thereby providing the ability to infect most mammalian cell types with high efficiency, regardless of proliferation state. Furthermore, the use of inducible promoters to drive shRNA expression allows for more thorough investig...
作者:Masayoshi Okada , Naaz Andharia , Hiroko Matsuda
来源:[J].BMC Neuroscience(IF 3), 2015, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br)High titers of lentiviral vectors are required for the efficient transduction of a gene of interest. During preparation of lentiviral the vectors, the protein of interest is inevitably expressed in the viral vector-producing cells. This expression m...
作者:Franziska K. Geis , Melanie Galla , Dirk Hoffmann ...
来源:[J].Retrovirology(IF 5.657), 2017, Vol.14 (1)Springer
摘要:Retroviral vectors are derived from wild-type retroviruses, can be used to study retrovirus-host interactions and are effective tools in gene and cell therapy. However, numerous cell types are resistant or less permissive to retrovirus infection due to the presence of active defe...
作者:Huanzhang Zhu , Xiaoguang Chen , Feng Li ...
来源:[J].Chinese Science Bulletin(IF 1.319), 2003, Vol.48 (20), pp.2196-2200Springer
摘要:Abstract(#br)To explore the expression of human clotting factor IX (hFK) cDNA in vitro and the feasibility of gene therapy for hemophilia B mice mediated by recombinant lentiviral vector, a recombinant hFK lentiviral vector driven by ubiquitin-C promoter, FUXW, and by ABP liver s...
作者:Zhang C , Dong WB , Zhao S ...
来源:[J].Drug Design, Development and Therapy(IF 3.486), 2016, Vol.Volume 10, pp.2611-2622DOAJ
摘要:Chan Zhang, Wen-Bin Dong, Shuai Zhao, Qing-Ping Li, Lan Kang, Xiao-Ping Lei, Lin Guo, Xue-Song Zhai Department of Newborn Medicine, Affiliated Hospital of Luzhou Medical College, Luzhou, Sichuan, People’s Republic of China Background: The aim of this study is to observe the inhibitive effects of p66Shc gene interfering lentivirus vectors...
作者:Stéphanie Durand , Andrea Cimarelli
来源:[J].Viruses(IF 2.509), 2011, Vol.3 (2), pp.132DOAJ
摘要:... In this review, we shall describe the main basic aspects of the virology of lentiviruses that were exploited to obtain efficient gene transfer vectors. In addition, we shall discuss some of the hurdles that oppose the efficient genetic modification mediated by lentiviral vectors...
作者:Felix F. Adams , Dirk Heckl , Thomas Hoffmann ...
来源:[J].Biomaterials(IF 7.604), 2017, Vol.139, pp.102-115Elsevier
摘要:... We combined a human miR-30 backbone retaining native flanking sequences with an optimized all-in-one lentiviral vector system for conditional RNAi to generate a versatile toolbox characterized by higher doxycycline sensitivity, reduced leakiness and enhanced titer. Furthermor...
作者:Ioanna Eleftheriadou , Michael Dieringer , Xuan Ying Poh ...
来源:[J].Biomaterials(IF 7.604), 2017, Vol.123, pp.1-14Elsevier
摘要:Abstract(#br)Lentiviral vectors are gene delivery vehicles that integrate into the host genome of dividing and non-dividing mammalian cells facilitating long-term transgene expression. Lentiviral vector versatility is greatly increased by incorporating heterologous viral envelope...
作者:Shiyong XU
来源:[J].Current Zoology(IF 1.392), 2009, Vol.55 (5)DOAJ
摘要:We demonstrated the simple and effective production of transgenic chickens,in which the enhanced green fluorescence protein (EGFP) was expressed by using third-generation self-inactive HIV-based lentiviral vectors. In our experiments, lentiviruses were injected into 204 fe...

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