全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Munisamy-Naidu Vinuthinee-Naidu , Embong Zunaina , Anuar Azreen-Redzal ...
来源:[J].BMC Ophthalmology(IF 1.444), 2017, Vol.17 (1)Springer
摘要:Uric acid is a final breakdown product of purine catabolism in humans. It’s a potent antioxidant and can also act as a pro-oxidant that induces oxidative stress on the vascular endothelial cells, thus mediating progression of diabetic related diseases. Various epidemiologic...
作者:Geetha Chittoor , Karin Haack , Nitesh R. Mehta ...
来源:[J].BMC Medical Genetics(IF 2.536), 2017, Vol.18 (1)Springer
摘要:Reduced renal excretion of uric acid plays a significant role in the development of hyperuricemia and gout in adults. Hyperuricemia has been associated with chronic kidney disease and cardiovascular disease in children and adults. There are limited genome-wide association studies...
作者:Yi Zhang , Yang Cui , Xuan-an Li ...
来源:[J].BMC Musculoskeletal Disorders(IF 1.875), 2017, Vol.18 (1)Springer
摘要:The aim of this study was to examine the associations of tea consumption with the serum uric acid (SUA) level, hyperuricemia (HU) and the risk of gout.
作者:Shuolin Wu , Yuesong Pan , Ning Zhang ...
来源:[J].BMC Neurology(IF 2.564), 2017, Vol.17 (1)Springer
摘要:Conflicting results on the correlation between hyperuricemia and the prognosis of stroke had been reported and the close association between serum uric acid (SUA) and abnormal glycomatabolism might further complicate the assessment of the correlation. We aimed to investigate SUA ...
作者:Xuling Chen , Ying Meng , Jun Li ...
来源:[J].BMC Ophthalmology(IF 1.444), 2017, Vol.17 (1)Springer
摘要:... This study aimed to explore the correlation between serum uric acid (SUA) concentration and hypertensive retinopathy in hypertensive adults.
作者:Miao Liu , Jianhua Wang , Jing Zeng ...
来源:[J].BMC Neurology(IF 2.564), 2017, Vol.17 (1)Springer
摘要:To evaluate the association between SUA levels within a normal to high range and the risk of mild cognitive impairment (MCI) among community elderly.
作者:Xuedong Ding , Manman Li , Chenglu Peng ...
来源:[J].BMC Veterinary Research(IF 1.861), 2019, Vol.15 (1), pp.1-12DOAJ
摘要:Abstract Background Breast cancer resistance protein (BCRP) and multidrug resistance protein 4 (MRP4) are involved in uric acid excretion in humans and mice. Despite evidence suggesting that renal proximal tubular epithelial cells participate in uric acid excretion in chickens, t...
作者:Giancarlo Bilancio , Pierpaolo Cavallo , Cinzia Lombardi ...
来源:[J].BMC Nephrology(IF 1.644), 2019, Vol.20 (1), pp.1-9DOAJ
摘要:... Previous reports indicated that creatinine, uric acid, and potassium are measurable in saliva. For these analytes the study investigated methodology of saliva tests and correlations between plasma and saliva levels. Methods The study enrolled 15 healthy volunteers for meth...
作者:Shen Z , Gillen M , Miner JN ...
来源:[J].Drug Design, Development and Therapy(IF 3.486), 2017, Vol.Volume 11, pp.2077-2086DOAJ
摘要:..., San Diego, CA, 2AstraZeneca, Gaithersburg, MD, USA Purpose: Verinurad (RDEA3170) is a selective uric acid reabsorption inhibitor in clinical development for the treatment of gout and asymptomatic hyperuricemia. The aim of this study was to evaluate the pharmacokinetics,...
作者:Hiroshi Arakawa , Natsumi Amezawa , Tomomichi Katsuyama ...
来源:[J].Drug Metabolism and Pharmacokinetics(IF 2.071), 2019, Vol.34 (2), pp.155-158Elsevier
摘要:Abstract(#br)The inhibitor of uric acid reabsorptive transporter URAT1 in kidney is drawing attention as a drug target for hyperuricemia. However, it is difficult to evaluate efficacy of URAT1 inhibitors in vivo using laboratory animals due to species difference in uric acid meta...

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