全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Kong Fanfei , Yang Hui
来源:[J].Cell death & disease(IF 6.044), 2018, Vol.9 (3), pp.303PubMed
摘要:Long noncoding RNAs (lncRNAs) have been implicated in tumorigenesis and cancer progression and are tightly associated with the phenotypes of numerous cancers. However, the functional roles underlying these effects are unknown. The expression levels of LINC01016, miR-302a-3p, miR-...
作者:Kong Fanfei , Dong Yishan ...
来源:[J].Nature communications(IF 10.015), 2016, Vol.7, pp.11406PubMed
摘要:Immune checkpoint blockade of the inhibitory immune receptors PD-L1, PD-1 and CTLA-4 has emerged as a successful treatment strategy for several advanced cancers. Here we demonstrate that miR-424(322) regulates the PD-L1/PD-1 and CD80/CTLA-4 pathways in chemoresistant ovarian canc...
作者:Kong Fanfei , Jiang Bing-Hua ...
来源:[J].Oncotarget(IF 6.636), 2015, Vol.6 (28), pp.26457-71PubMed
摘要:The mechanism of cisplatin resistance in ovarian cancer is not clearly understood. In the present investigation, we found that the expression levels of miR-497 were reduced in chemotherapy-resistant ovarian cancer cells and tumor tissues due to hypermethylation of miR-497 promote...
作者:Kong Fanfei , Han Lingfei
来源:[J].Gynecologic and obstetric investigation, 2016, Vol.81 (1), pp.61-70PubMed
摘要:Human papillomavirus type 16 (HPV16) is the cause of more than half of all cases of cervical cancer. Genetic mutations in HPV16 and the integration of HPV16 DNA in the human genome are considered important genetic changes in cervical lesion progression. However, limited data conc...
作者:Kong Fanfei , Ma Jian ...
来源:[J].Biochimica et biophysica acta, 2018PubMed
摘要:The plasmacytoma variant translocation 1 (PVT1)1 gene is a long non-coding RNA (lncRNA)2 that has been shown to be an oncogene in many cancers. Herein, the function and potential molecular mechanisms connecting PVT1 and miR-195-5p were elucidated in endometrial cancer cell lines....
作者:Kong Fanfei , Sun Chaoyang ...
来源:[J].Huazhong University of Science and Technology. Journal (Medical Sciences)(IF 0.581), 2011, Vol.31 (4), pp.543-9PubMed
摘要:Chemotherapy is the preferred therapeutic approach for advanced ovarian cancer, but a successful long-term treatment is prevented by the development of drug resistance. Recent works have underlined the involvement of non-coding RNAs, microRNAs (miRNAs) in cancer development, with...

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