全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Zhao Lixun , Jiang Jiandong , Cen Shan
来源:[J].Retrovirology(IF 5.657), 2011, Vol.8 (1), pp.2DOAJ
摘要:Abstract Background Human APOBEC3G (hA3G) has been identified as a cellular inhibitor of HIV-1 infectivity. Viral incorporation of hA3G is an essential step for its antiviral activity. Although the mechanism underlying hA3G virion encapsidation has been investigated extensively, ...
作者:... He Jian , Li Shunpeng , Jiang Jiandong
来源:[J].Applied and Environmental Microbiology(IF 3.678), 2015, Vol.81 (23), pp.8084-8092The Royal Society
摘要:The 3-phenoxybenzoate (3-PBA) 1′,2′-dioxygenase gene cluster ( pbaA1A2B cluster), which is responsible for catalyzing 3-phenoxybenzoate to 3-hydroxybenzoate and catechol, is inducibly expressed in Sphingobium wenxiniae strain JZ-1T by its substrate 3-PBA. In this ...
作者:... Lin Huandong , Jiang Jiandong , Gao Xin
来源:[J].Journal of translational medicine(IF 3.459), 2016, Vol.14, pp.266PubMed
摘要:We recently demonstrated a positive effect of berberine on nonalcoholic fatty liver disease patients after 16 weeks of treatment by comparing mere lifestyle intervention in type 2 diabetes patients with berberine treatment, which decreased the content of hepatic fat. However, the...
作者:... Li Wenbin , Jiang Jiandong , Chen Xiaoguang
来源:[J].Scientific reports(IF 2.927), 2017, Vol.7, pp.39011PubMed
摘要:Glioblastoma is an aggressive tumor that is associated with distinctive infiltrating microglia/macrophages populations. Previous studies demonstrated that chlorogenic acid (5-caffeoylquinic acid, CHA), a phenolic compound with low molecular weight, has an anti-tumor effect i...
作者:Jiang Jiandong , Li Zhuorong
来源:[J].Virology journal(IF 2.092), 2017, Vol.14 (1), pp.145PubMed
摘要:Human papillomaviruses (HPVs) are the primary causative agents for cervical cancer, and HPV oncoproteins E6 and E7 are known to be the main reason for the onset and maintenance of the malignancies. Therefore, inhibition of viral E6 and E7 oncoproteins expression represents a viab...
作者:... Li Zhuorong , Jiang Jiandong , Li Yuhuan
来源:[J].Virology journal(IF 2.092), 2017, Vol.14 (1), pp.55PubMed
摘要:Influenza virus is still a huge threat to the world-wide public health. Host inosine-5'- monophosphate dehydrogenase (IMPDH) involved in the synthesis of guanine nucleotides, is known to be a potential target to inhibit the replication of viruses. Herein, we evaluated antiviral a...
作者:... Yan Haiyan , Jiang Jiandong , Li Yuhuan
来源:[J].Virology journal(IF 2.092), 2017, Vol.14 (1), pp.2PubMed
摘要:The MEK-ERK signaling pathway and autophagy play an important role for enterovirus71(EV71) replication. Inhibition of MEK-ERK signaling pathway and autophagy is shown to impair EV71 replication. Berberine (BBR), an isoquinoline alkaloid isolated from Berberis vulgaris L., has bee...
作者:Jiang Jiandong , Jiang Wei
来源:[J].Journal of Antimicrobial Chemotherapy, 2015, Vol.70 (8), pp.2287-2294The Royal Society
摘要:Objectives Drug-resistant Mycobacterium tuberculosis poses a great threat to human health. Tyrosyl-tRNA synthetase (TyrRS) is one of the aminoacyl tRNA synthetases that catalyse the attachment of amino acids to their cognate tRNAs and are essential for protein synthesis. There ar...
作者:Jiang Jiandong , Wang Yanchang
来源:[J].Oncotarget(IF 6.636), 2017, Vol.8 (1), pp.1234-1246PubMed
摘要:Polo-like kinase 1 (Plk1) is a promising target for cancer therapy due to its essential role in cell division. In addition to a highly conserved kinase domain, Plk1 also contains a Polo-Box domain (PBD), which is essential for Plk1's subcellular localization and mitotic functions...

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