全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Guo Fengjing , Yang Qing
来源:[J].International journal of molecular sciences(IF 2.464), 2016, Vol.17 (6)PubMed
摘要:Previous studies showed that SDF-1α is a catabolic factor that can infiltrate cartilage, decrease proteoglycan content, and increase MMP-13 activity. Inhibiting the SDF-1α/CXCR4 signalling pathway can attenuate the pathogenesis of osteoarthritis (OA). Recent studies have als...
作者:Guo Fengjing , Wang Taiyi ...
来源:[J].Journal of Tongji Medical University, 2000, Vol.20 (3), pp.242-245Springer
摘要:Summary(#br)In order to investigate the bovine calcined bone’s ability of repairing segmental bone defect and seek a new artificial bone substitute material, the bovine calcined bone (450°C, 32 h) was implanted into the 10-mm middle radial defect of rabbits with tricalcium p...
作者:Guo Jiachao , Sun Kai ...
来源:[J].Frontiers in pharmacology, 2019, Vol.10, pp.163PubMed
摘要:Iron overload has been reported to contribute to bone marrow mesenchymal stem cells (BMSCs) damage, but the precise mechanism still remains elusive. Icariin, a major bioactive monomer belonging to flavonoid glucosides isolated from Herba Epimedii, has been shown to protect c...
作者:Guo Jiachao , Li Weijin ...
来源:[J].Frontiers in pharmacology, 2017, Vol.8, pp.693PubMed
摘要:Pregnane X receptor (PXR) which belongs to the nuclear hormone receptor superfamily plays vital roles in several biological functions, especially in the inflammatory procedure. Besides that, PXR is revealed by recent studies to have essential effects on bone tissue. As an ag...
作者:Guo Jiachao , Li Weijin ...
来源:[J].Frontiers in pharmacology, 2017, Vol.8, pp.991PubMed
摘要:[This corrects the article on p. 693 in vol. 8, PMID: 29046637.].
作者:... Sun Kai , Guo Fengjing , Xu Tao
来源:[J].Life sciences, 2019PubMed
摘要:AIMS(#br)Biomechanical reactivity is a special property of chondrocytes and mechanical stress can affect the development of cartilage. Primary cilia have been proved a cellular sensory which can detect physical and chemical stimuli extracellular and initiate multiple signaling tr...
作者:Guo Fengjing , Wu Gang ...
来源:[J].Journal of cellular biochemistry, 2019, Vol.120 (9), pp.15397-15409PubMed
摘要:Osteosarcoma is one of the most malignant tumors in adolescents with severe outcomes while fluoride is one of the most abundant elements in the environment. Epidemiological evidence has elucidated the relationship between fluoride and osteosarcoma, but the molecular mechanisms ar...
作者:Guo Jiachao , Xiang Wei ...
来源:[J].Journal of cellular physiology, 2019, Vol.234 (7), pp.10123-10137PubMed
摘要:Iron overload is common in patients with diseases such as hemoglobinopathies, hereditary hemochromatosis or elderly men and postmenopausal women. This disorder is frequently associated with bone loss and recently has been considered as an independent risk factor for osteoporosis....
作者:... Tang Aimin , Guo Fengjing , Xie Weigui
来源:[J].Soft matter, 2019PubMed
摘要:The scaffold is one of the most important components in tissue engineering. There are a lot of natural or synthetic materials applied for the fabrication of scaffolds. Among them, cellulose nanofibril (CNF) is an important natural polymer with characteristics of superior biocompa...
作者:... Li Feng , Guo Fengjing , Chen Anmin
来源:[J].Biochemical and biophysical research communications, 2016, Vol.474 (2), pp.296-302PubMed
摘要:Osteoarthritis (OA) is one of the most progressive articular cartilage erosions. microRNAs (miRNAs) play pivotal roles in OA modulation, but the role of miR-139 in OA remains elusive. This study aims to reveal the effects and possible mechanism of miR-139 in OA and chondrocytes. ...

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